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"If thou canst cuckold him, thou dost thyself a pleasure, me a sport."

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Here Iago explains how Roderigo can help him. He knows that Roderigo lusts after Desdemona and is angry to learn that she is married Othello. Iago encourages Roderigo to believe that by participating in Iago’s plot, he might have the chance to have an affair with Desdemona, but in reality he is just using Roderigo.

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Iago used Desdemona and took advantage of her innocence to provoke Othello

Iago gives Othello the impression that Cassio and Desdemona might be having an affair, Othello becomes extremely envious and suspicious when Desdemona does step in on Cassio's behalf. Together with other anxieties Iago has l put upon him this enrages Othello.

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Iago convinces Cassio to confide with Desdemona to help with getting his position of Lieutenant back, as he knows she has great influence on Othello.

"Our general's wife is now the general . . . Confess yourself freely to her, importune her help to put you in your place again." (Act II, Scene 3)

This eventually is foreshadowing how Iago will use this as a reason as to why Othello should be suspicious of Desdemona.

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"And what would you give me now for the same handkerchief?" 

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Iago convinces Emilia to steal Desdemona's special handkerchief for him. This shows that Iago takes advantage of Emilia and appreciates her only when she serves him. She, however, thinks he's loyal to her and so she obeys him.

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"She did deceive her father, marrying you."

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Iago says this as a way of going against Othello’s insistence that Desdemona is honest and would not lie to him. He points out that Desdemona has the capacity to lie and keep secrets since she hid her marriage with Othello from her disapproving father. This quote shows Iago’s skill at psychological manipulation: he subtly plants a seed of doubt in Othello’s mind, using the couple’s own love as a weapon to increase the distrust between them.

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Iago manipulates, uses and takes advantage of people. He does this to get what he wants. One way he exploits people is by tricking them into believing they get something out of it like with Roderigo. A second way is by deceiving them that he is the honest Iago so they will believe anything he says like Othello. A third way is making them believe it was their idea, therefore does not get blamed and still gets what he wants like Cassio. Regardless of how he does it Iago will always benefit from the situation .