# data[].attributes.body
Scott syndrome
Microparticules
phosphatidylserine
procoagulation
flippase
floppase
scramblase

ca2+
remodeling
asymetry
membrane
vesicles

Références:
T.Lhermusier, H.Chap, B. Payrastre (2011)

Platelet membrane phospholipid asymmetry: from the characterization of a scramblase activity to the identification of an essential protein mutated in Scott syndrome. jth 9 (10): 1883–1891

D. Kerbiriou-Nabias, D. Geldwerth-Feniger (2007) Exposition membranaire

de la phosphatidylsérine

et activité procoagulante

des plaquettes. Hématologie 13(2) : 94-109

Allen RD, Schroeder CC, Fok AK, (1989)

An investigation of mitochondrial inner membranes by rapid-freeze deep-etch techniques. J CELL BIOL 108 (6): 2233

# data[].attributes.body
Key-words :
Clathrine - recrutement - membrane (CCP) - endocytosis - AP - vesicules - transmembrane receptors -  ARF6

References :

1. Krauss M, Kinuta M, Wenk MR, De Camilli P, Takei K, Haucke V(2003) ARF6 stimulates clathrin/AP-2 recruitment to synaptic membranes by activating phosphatidylinositol phosphate kinase type Iγ JCB : DOI: 10.1083/jcb.200301006

2. Boulakirba S, Macia E, Partisani M, Lacas-Gervais S, Frédéric Brau, Luton F andFranco M Arf6 exchange factor EFA6 and endophilin directly interact at the plasma membrane to control clathrin-mediated endocytosis PNAS 2014 July, 111 (26): 9473-9478. https://doi.org/10.1073/pnas.1401186111

# data[].attributes.body
cargo proteins
endocytosis
clathrin independent

caveolae
IL2-R(β)
CLIC/GEEC
flotillin
Arf6
Shiga Toxin

Ref :
Liu J, Sun Y, Drubin DG, Oster GF. The mechanochemistry of endocytosis. PLoS Biol 2009 ; 7 : e1000204.

E. Boucrot, A. P. A. Ferreira, L. Almeida-Souza, S. Debard, Y. Vallis, G. Howard, L. Bertot, N. Sauvonnet, H. T. McMahon (2015) Endophilin marks and controls a clathrin-independent endocytic pathway. Nature 517 (1)460–465

ref exercice:
Allen RD , Schroeder CC , Fok AK  (1989), An investigation of mitochondrial inner membranes by rapid-freeze deep-etch techniques. J Cell Biol 108 (6): 2233-2240

# data[].attributes.body
RCPG
ligand
pharmacologie
overexpression
stabilisation
purification
extraction
solubilisation

Références:
Shibata Y, White JF, Serrano-Vega MJ, et al. Thermostabilization of the neurotensin receptor NTS1. J Mol Biol 2009 ; 390 : 262-7.

Daniel Boujard (2015) Production de protéines recombinantes. Biologie Moléculaire et Cellulaire, ed. DUNOD, 2e édition : 144-145

Biblio:
Allen RD, Schoreder CC, Fok AK (1989) An investigation of mitochondrial inner membranes by rapid-freeze deep-etch techniques, J CELL BIOL 108 (6): 2233-2240

# data[].attributes.body
membrane compartments
cystic fibrosis

références
Y. Yang, S janich, J A Cohn, J M Wilson (1993) The common variant of cystic fibrosis transmembrane conductance regulator is recognized by hsp70 and degraded in a pre-Golgi nonlysosomal compartment, Proc Nati Acad Sci USA 90 (20): 9480-9484
D. Hubert (2016) Nouvelles thérapeutiques de la mucoviscidose ciblant le gène ou la protéine CFTR, Revues des maladies respiratoires 33 (8): 0761-8425

Allen RD, Schroeder CC, Fok AK (1989) an investigation of mitochondrial inner membranes by rapid-freeze deep-etch techniques, J CELL BIOL 108 (6): 2233-2240

# data[].attributes.body
Membrane fusion
synapse connexion
neurotransmitters
proteins
SNARE complex
syntaxine
synaptotagmine
synaptobrévine
NSF / SNAP
vesicle
brain

références :

Lledo, P. M., Zhang, X., Südhof, T. C., Malenka, R. C. & Nicoll, R. A. Postsynaptic membrane fusion and long-term potentiation. Science 279, 399 ?403 (1998).

Rothman, James Edward.  Le principe de la fusion membranaire dans la cellule (2015)

LTP Requires a Unique Postsynaptic SNARE Fusion Machinery
Jurado, Sandra 1, 5
Goswami, Debanjan 1, 5
Zhang, Yingsha 2
Molina, Alfredo J. Miñano 1, 4
Südhof, Thomas C. 2, 3
Malenka, Robert C. 1, ∗

In Neuron 6 February 2013 77(3):542-558

Published: February 6, 2013
0896-6273

Biblio :

Allen RD, Schroeder CC, Fok AK
(1989 )

An investigation of mitochondrial inner membranes by rapid-freeze deep-etch techniques.

108 (6) : 2233-2240