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Solid phase extraction can be used in cases involving arson and terrorism. After evidence from a crime scene is brought back to the lab, technicians find that some of the explosive residues have mixed with and dissolved in an unknown solution. The technician used the SPE procedure to isolate the residue from the solution. This residue is later put into a mass spectrometer and found to be the explosive used in the crime. After further testing and comparison, the same substance was found at a house belonging to a suspected terrorist

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It can be used to clean up a sample before using a chromatographic or other analytical method to identify the amount of analyte(s) in the sample.

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This tool has the ability to analyze and identify different substances such as: blood, urine, water, beverages, compounds, and soils

SPE can also identify explosive residues because no heat is required.

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Solid phase extraction is an extraction method that uses a solid phase and a liquid phase to isolate one analyte from a solution.

A solid phase manifold separates dissolved substances from other components in the mixture based on their chemical properties.