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Pub chem with chemical structure and names.

https://pubchem.ncbi.nlm.nih.gov/compound/Cocaine#section=Crystal-Structures

Apa: Cocaine. (n.d.). Retrieved October 15, 2020, from https://pubchem.ncbi.nlm.nih.gov/compound/cocaine

American Addiction Center with street names

https://americanaddictioncenters.org/cocaine-treatment/slang-names

Short Term effects from National Institute on Drug Abuse

https://www.drugabuse.gov/publications/research-reports/cocaine/what-are-short-term-effects-cocaine-use

Apa:

NIDA. 2020, May 28. What are some ways that cocaine changes the brain? . Retrieved from https://www.drugabuse.gov/publications/research-reports/cocaine/what-are-some-ways-cocaine-changes-brain on 2020, October 15

Lethal Dose of Cocaine by Sunshine Behavioral Health

https://www.sunshinebehavioralhealth.com/stimulants/how-deadly-is-cocaine/

Apa: How Deadly Is Cocaine?: Can Cocaine Kill You Instantly?: Learn More. (n.d.). Retrieved October 15, 2020, from https://www.sunshinebehavioralhealth.com/stimulants/how-deadly-is-cocaine/

Book/Article by John R. Richards about cocaine toxicity (3 stages).

https://www.ncbi.nlm.nih.gov/books/NBK430976/

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1. Cocaine fills the body with dopamine.
The pleasure that comes from cocaine is due to the neurochemical reactions it produces in the brain. Cocaine blocks the reabsorption of dopamine – which is responsible for feelings of pleasure and euphoria.

2. Anyone can become addicted to cocaine.
Just like any other drug, cocaine doesn’t discriminate. One out of four Americans between the ages of 26 and 34 reportedly use cocaine at some point in their lives, and these people come from all walks of life.

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While there are some legal elements of cocaine in some countries around the world, there is no real legality of the use of cocaine, especially in the U.S.

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Cocaine is rarely used in the medical field. Cocaine can act as a particularly effective local anesthetic that works by blocking nerve impulses. Cocaine is also used during procedures involving the upper respiratory tract. However, there are no proven benefits for the use of cocaine on the streets illegally.

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Through what is simply called a cocaine screen. This test can be done on urine, saliva, blood, hair, or sweat. It looks for the presence of cocaine or one of its metabolites. The results come back in just minutes.

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What is the treatment following an overdose?

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What is the treatment following an overdose?

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Untreated, an overdose can be fatal. If caught early, a reversal is fairly simple. If the person is seizing, you must put them on their side in a safe and open place, to avoid the person hitting their head or limbs. Apply a cold compress to the person's forehead, neck, and wrists to reduce body temperatures. Once medical personnel arrives, the patient will be rushed to the ER where they will be given multiple medications and fluid to reverse the effects of the overdose. If not treated soon enough, these overdoses can easily result in death.

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How long does the drug stay in your body?

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How long does the drug stay in your body?

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The basic effects of cocaine shown in this graph--high, craving, rush, and low-- all tend to cease after about 20 minutes for most people.

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Experts say that there are THREE stages of Acute Cocaine Toxicity. In the first stage, or low toxicity, symptoms include headache, nausea, twitching, feeling paranoid, aggressive and confused. In stage 2 of acute toxicity or somewhat in the middle of low and high, users can start to have seizures, cardiac hypertension, and irregular or trouble breathing. Finally, in the third stage of acute toxicity, or the High end of the spectrum, symptoms include coma, dilated pupils, loss of vital functions, cardiac arrest, and respiratory failure. These are all things that are dangerously nearing death and would require medical attention immediately.

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Cocaine, or also commonly known as crack, blow, coke, nose candy. The scientific name or the IUPAC name is methyl (1R,2R,3S,5S)-3-benzoyloxy-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate

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There are long term affects to the brain that comes with the use of cocaine. Researchers have found that cocaine exposure can cause adaptations in neurons that release excitatory neurotransmitter glutamate. In a study on animals who were chronically exposed to cocaine, they demonstrate changes in glutamate neurotransmission. "The glutamate system may be an opportune target for anti-addiction medication development, with the goal of reversing the cocaine-induced neuroadaptations that contribute to the drive to use the drug," (National Institution on Drug Abuse).

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What are the effects on the body of Cocaine?

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What are the effects on the body of Cocaine?

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Cocaine users shortly following a single dose will feel euphoric, energetic, talkative, and make the user hypertensive to sight, sound, and touch. The drug then also temporarily reduces the need for food and sleep. Cocaine can affect the cardiovascular system by increasing the heart rate. Cocaine can affect the vascular or circular system by severely increasing blood pressure.

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How much Cocaine can you take before it turns lethal?

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How much Cocaine can you take before it turns lethal?

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The difference between a desired dose and a lethal dose of cocaine is very hard for users to determine. Users are on very thin ice, with many different factors affecting how much you can take. It is not uncommon for users to have an overdose to really find out their limit. This limit varies from person to person. It can depend on a number of things, such as your medical history, the purity or toxicity of the cocaine, whether other opioids have been added (which is very common), and also the tolerance each user has built. Some people say it comes down to pure luck.

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Cocaine is a stimulant drug, which means that the drug increases feeling of energy and suppresses appetite.