# data[].attributes.body
- look up on drug handbook whether the drug is safe to use in pregnancy / breastfeeding
- Novorapid is safe to use in Pregnancy !

# data[].attributes.body
- closely monitor patient
- adjust the dose

Omeprazole is safe during pregnancy

# data[].attributes.body
Note: Always consider:
Is there anything in the patient's condition/ past history that may increase the risks?

# data[].attributes.headline
Pregnant and breast feeding patients and medications

# data[].attributes.subject
Pregnant and breast feeding patients and medications

# data[].attributes.body
1. What steps should the nurse take prior to administering medicines to a pregnant or breastfeeding patient?

Look up the prescribed medications to see if they are safe to administer.
Remember there may be an additional resource that you may want to access

# data[].attributes.body
Metformin
MOA: Reduces production of glucose in the liver and increases peripheral utilisation of glucose
Indications: Type 2 diabetes
Signs & Symptoms: nausea, vomiting, anorexia, diarrhoea
Drug - drug interactions: Dolutegravir
Nursing considerations/how to prevent, identify/manage risks
- Use with caution in patients with decreased renal function
- Avoid use in severe hepatic impairment

# data[].attributes.body
Optisulin
MOA: lower blood glucose by stimulating peripheral glucose intake, by skeletal muscles and fat, and inhibits hepatic glucose production.
Indications:

Signs & Symptoms:

Redness, rash, itching, wheezing, difficult breathing, facial swelling or hives, hypoglycemic attacks, neurological damage, weight gain
Drug - drug interactions:
oral antidiabetic dugs for type 2 diabetes, antihypertensive, anti-inflammatory, analgesics, sulfonamides antibiotics  and antidepressants.
Nursing considerations/how to prevent, identify/manage
risks:
1. do not dilute
2. do not mix with any other insulin
3. Do not inject on bruised or tender skin
4. Regular monitoring of blood glucose
5. check insulin pump

# data[].attributes.attachment_caption
What would they be for this medication chart?

# data[].attributes.headline
Significant risks / drug-drug interactions???

# data[].attributes.subject
Significant risks / drug-drug interactions???

# data[].attributes.body
How / why does it occur?
What are they and what signs and symptoms would we see?
What do we as nurses do;
- prevent and/ or manage these?

# data[].attributes.body
Novorapid
MOA: Increase or restore ability to metabolise glucose by enhancing cellular glucose uptake
Indications: diabetes mellitus (I or II) or GD
Signs & Symptoms: safe to use in pregnancy
(!!)hypoglycemia, weight gain, local reactions (to injection)

Drug - drug interactions:
Metformin: ok to have both in use although insulin may need to be adjusted
Optisulin: is a long acting, do not mix this with novorapid when injecting.
Nursing considerations/how to prevent, identify/manage risks
Short acting insulin, fast onset.
Give immediately before meals
May be allergies or local reactions to injections- consider switching types of insulin.
Monitor BGL, take BGL reading before administering

# data[].attributes.headline
Compare and contrast the mode of action of the drug classes

# data[].attributes.subject
Compare and contrast the mode of action of the drug classes

# data[].attributes.body
Did you find a simpler way to describe them?
Could you say in your own words what they are?
Did you need to go and look them up again? Do you need to rethink your explanation into your own words?

# data[].attributes.body
Metoclopramide
Classification: Gastrointestinal agent
MOA: inhibition of presynaptic and postsynaptic D2 receptors and sensitise GI smooth muscle to effects of acetylcholine by direct action.
Indications: Gastroesophageal reflux diseases, chemotherapy induced emesis

Signs & Symptoms: restlessness, drowsiness, fatigue, insomnia, anxiety, diarrhoea
Drug - drug interactions: Digoxin, acetaminophen, tetracycline, levodopa
Nursing considerations/how to prevent, identify/manage risks

- Monitor BP carefully during IV administration.
- Monitor diabetic patients, arrange for alteration in insulin dose.
- Ask patient to be alert and report immediately about the warning signs like, onset of restlessness, involuntary movements, facial grimacing, rigidity, or tremors.
- Monitor for possible hypernatremia and hypokalemia

# data[].attributes.body
Omeprazole
MOA: Bind to the hydrogen/potassium ATPase enzyme system (proton pump), inhibiting both stimulated and basal acid secretion.
Indications:
- peptide ulcer disease
- GORD
- Zollinger-Ellison syndrome (rare digestive disorder - too acid in stomach)
- H. pylori eradication (bacterial infection in stomach)
Signs & Symptoms:
- headache
- N+V
- diarrhoea
- abdo pain
- constipation
- flatulence
Drug - drug interactions:
- digoxin
- not on any drugs that interacts with it
Nursing considerations/how to prevent, identify/manage risks:
- avoid foods that may cause GI irriations (like spicy foods)
- avoid alcohol
- allow 2hrs inbtw meds