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COVID-19 is a type of coronavirus caused by SARS-Cov 2. Coronavirus is the disease thsat predominantly targets the respiratory system. It is similar to SARS and MERS virus. Based on genetic sequence identity And phylogenetic reports COVID-19 is considered as a new beta coronavirus that infect human.

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The 1st case was reported in Wuhan, China in December 2019. A bunch of patients were submitted at the hospital with respiratory infection from an unknown source. However, they were linked back to a seafood and wet animal wholesale market in Wuhan, China. From December 18th-29th, 2019 five patients were hospitalized with respiratory infection and one of them died. By January 2nd, 2020 fourth one patients admitted and half of them had underlying health conditions such as diabetes, hypertension, and cardiovascular disease. By January 22nd, 2020 China National Health Commission reported 17th deaths. Only within 3 days 1975 cases were confirmed and 56 deaths in mainland China. By January 30th ninety other cases were confirmed in other countries like Taiwan, Thailand, Vietnam, Malaysia, UAE, Canada,Australia and many more. The 1st human to human transmission of COVID-19 at US was in January 30th, 2020.

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The most common symptoms are cough, fever and shortness of breath. There are other symptoms such as sputum production, headache, haemoptysis, diarrhea, dyspnoea, lymphopenia, pneumonia, RNAaemia, acute respiratory distress syndrome, acute cardiac injury and incidence of ground glass opacities were observed in subpleural regions of both lungs.

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The English version was updated on 20 October 2020

COVID-19 is caused by the SARS-CoV-2 virus, which spreads between people, mainly when an infected person is in close contact with another person.

The virus can spread from an infected person's mouth or nose in small liquid particles when they cough, sneeze, speak, sing or breathe heavily. These liquid particles are different sizes, ranging from larger 'respiratory droplets' to smaller 'aerosols'.

Other people can catch COVID-19 when the virus gets into their mouth, nose or eyes, which is more likely to happen when people are in direct or close contact (less than 1 metre apart) with an infected person.

Current evidence suggests that the main way the virus spreads is by respiratory droplets among people who are in close contact with each other.

Aerosol transmission can occur in specific settings, particularly in indoor, crowded and inadequately ventilated spaces, where infected person(s) spend long periods of time with others, such as restaurants, choir practices, fitness classes, nightclubs, offices and/or places of worship. More studies are underway to better understand the conditions in which aerosol transmission is occurring outside of medical facilities where specific medical procedures, called aerosol generating procedures, are conducted.

The virus can also spread after infected people sneeze, cough on, or touch surfaces, or objects, such as tables, doorknobs and handrails. Other people may become infected by touching these contaminated surfaces, then touching their eyes, noses or mouths without having cleaned their hands first.
Find out more about the science about how the SARS-CoV-2 virus infects the body and how our body's immune system reacts by watching or reading this interview with WHO's technical lead for COVID-19, Dr Maria Van Kerkhove.

Whether or not they have symptoms, infected people can be contagious and the virus can spread from them to other people.

Laboratory data suggests that infected people appear to be most infectious just before they develop symptoms (namely 2 days before they develop symptoms) and early in their illness. People who develop severe disease can be infectious for longer.

While someone who never develops symptoms can pass the virus to others, it is still not clear how frequently this occurs and more research is needed in this area.

Both terms refer to people who do not have symptoms. The difference is that 'asymptomatic' refers to people who are infected but never develop any symptoms, while 'pre-symptomatic' refers to infected people who have not yet developed symptoms but go on to develop symptoms later.

Any situation in which people are in close proximity to one another for long periods of time increases the risk of transmission. Indoor locations, especially settings where there is poor or no ventilation, are riskier than outdoor locations.

Transmission can occur more easily in the "Three C's":

Crowded places with many people nearby;

Close-contact settings, especially where people have conversations very near each other;

Confined and enclosed spaces with poor ventilation.

The risk of COVID-19 spreading is higher in places where these "3Cs" overlap.

In health facilities, some medical procedures, called aerosol generating procedures, can produce very small droplets (called 'droplet nuclei' or 'aerosols') that can stay suspended in the air for longer periods of time. This is why health workers performing these procedures take specific airborne protection measures, including using appropriate personal protective equipment, including respirators, and why visitors are not permitted in areas in which these procedures are being performed.

To limit the risks of getting COVID-19 follow these basic precautions:

Follow local guidance. Check to see what national, regional and local authorities are advising so you have the most relevant information for where you are.

Stay at least 1 metre away from others, even if they don't appear to be sick.

Wear a mask, especially when you can't physically distance.

Manage your risks by thinking about location and setting of the event, proximity to others and time you will be at the event. In other words, consider where you are going, how close you will be to other people and how long you will be there. Avoid crowded places and events, poorly ventilated indoor locations and prolonged contact with others.

Open windows when indoors to increase the amount of outdoor air.

Avoid touching surfaces, especially in public settings, because someone with COVID-19 could have touched them before. Clean surfaces regularly with standard disinfectants.

Frequently clean your hands with soap and water, or an alcohol-based hand rub. If you can, carry alcohol-based rub with you and use it often.

Cover your coughs and sneezes with a bent elbow or tissue, throwing used tissues into a closed bin right away. Then wash your hands or use an alcohol-based hand rub.

Read our public advice page for more information.

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Coronavirus disease (COVID-19): How is it transmitted?

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The English version was updated on 20 October 2020 COVID-19 is caused by the SARS-CoV-2 virus, which spreads between people, mainly when an infected person is in close contact with another person. The virus can spread from an infected person's mouth or nose in small liquid particles when they cough, sneeze, speak, sing or breathe heavily.

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COVID-19 infected patient showed higher leukocyte numbers, increased levels of plasma pro-inflammatory cytokines. The positive real time polymerase chain reaction on sputum confirmed COVID-19 infection. Moreover, C-reactive protein level was noted higher than normal. Some of the ICU patients cases showed high level of pre-inflammatory cytokines including IL2, IL7, GCSF, IP10, MCP1 and TNF that were the reason of severity.

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Centers for Disease Control and Prevention

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CDC provides credible COVID-19 health information to the U.S.