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LO1: Relate the pathogenesis and pathophysiology of measles to its clinical presentation
- Discuss on different types of rashes,
pattern of distribution, appearance
and resolution, and pathophysiology
- Relate the type and appearance of rashes with measles.🥹 Omar

- epidemiology, mode of transmission, clinical features, pathophysiology and complications of measles
- risk of materno-fetal transmission of infection and
development of congenital malformation😉 jim

-  pathophysiology of lethargy
- pathophysiology of dehydration and its severity
- pathophysiology of lymphadenopathy with fever in this patient😌 *Anisha*

- other causes of rashes in both
children and adults (infective and
non-infective cause)😶‍🌫️ Iman
--List other causes of viral exanthem
- Describe the epidemiology, pathogenesis, clinical features, and laboratory diagnosis for:
a) rubella virus
b) varicella zoster virus
c) herpesviruses
d) enteroviruses
e) measles virus
f) B19 parvovirus😆😆 pravei, alia

LO2: Interpret the investigation results of measles
Interpret and discuss the results:😘 Nafiz
- BUSE
- Random blood glucose
-    Blood culture
Discuss the relevance of doing
-dengue serology
-specific laboratory tests for measles
- other investigation etc  FBC, RT-PCR, histologic analysis of the rash(exanthem)

LO3: Discuss the psychosocial implication of measles
- immunisation and its principle
- Current immunisation schedule in Malaysia
- significance of immunisation history for this patient
- ethical concern with regards to immunisation🙊Fatiha
-psychosocial implication of the illness to the patient and family members in particular the pregnant mother and the unborn child. Include merci.😭 Sinehaa

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Laboratory investigations: BUSE : Urea 8, K+ 3.5, Na+ 140 Random blood glucose : 5.1 mmol/L (reference interval :< 11.1 mmol/L)
Blood culture : No growth
Measles serology : IgM Detected
Dengue serology : not detected
Patient was diagnosed with measles and was treated accordingly.

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-Ask where the rashes began?
-If red colour doesnt go when pressed means its dangerous
-blanching indicates restriction of blood flow

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High grade fever
Bp is normal
Hr is elevated due to fever

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-Mother is in 3rd trimester already
-infection can spread to the fetus
-can cause fetal complication

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-still not fully developed
- we can check of mark on injection on left sholder

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-Appeared on 3rd dayof fever
-Could hv relation with incubation period
-The could be a blister
-how much of area the rash covers
-could be a systemic problem
-if we press the rash and doesent turn white = dangerous
-difrrent patterns of rash indicate diffrent diagnosis

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-Fever not prolonged (acute)
-lethargy could be bcuz lack of nutrition

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-Elizabeth
-4yrs old
-female

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Elizabeth, a 4-year-old girl presented with high grade fever for 4 days associated with lethargy. Her mother noted the appearance of rash on day 3 of fever. She is the youngest of three siblings and her immunization status is unknown. Her mother is expecting the fourth child in one month.

On examination, the girl was moderately dehydrated. Her temperature was 39oC, blood pressure 90/70 mmHg and pulse rate 120 beats/min. Dull and red blanching rashes were noted over the face and neck. There was cervical lymphadenopathy. Examination of other systems was normal.