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Syphilis incubates for six weeks before lesions called chancre appear. Chancre are small and painless. While in males chancre appear on the penis, it tends to go unnoticed in women because the lesions appear on the inside of the vagina. Chancre normally heal within six weeks, but the second stage begins. The second stage's symptoms consist of a pink rash on the body, fever, joint pain, and sometimes hair loss.

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If syphilis goes untreated it can tun into tertiary syphilis. Tertiary syphilis can cause lesions on the brain and damage to the bones, cardiovascular organs, and joints. The damage caused can end up being fatal.

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Newborns who are infected can have many health problems including impaired hearing and vision. At first infected newborns may not have any symptoms. Antibiotics can be used to treat newborns who are infected.

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Around 50,000 people are infected in the United States a year.

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Antibiotics can be used to treat the infection but the damaged that was caused by the infection is can not be repaired.

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Syphilis is caused by the bacterium Treponema pallidum. Treponema pallidum is a bacterium that is spiral-shaped.