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A United States federal legislation that stopped northern attempts to forever prohibit slavery's expansion by admitting Missouri as a slave state and Maine as a free state in exchange for legislation which prohibited slavery in the remaining Louisiana Purchase lands north of the 36°30′ parallel except for Missouri.

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The Liberator begins publication (January 1, 1831)

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The Liberator begins publication (January 1, 1831)

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A weekly abolitionist newspaper, printed and published in Boston by William Lloyd Garrison and, through 1839, by Isaac Knapp.

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A rebellion of enslaved Virginians that took place in Southampton County, Virginia, in August 1831, led by Nat Turner.

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An armed conflict between the United States and Mexico from 1846 to 1848.

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A package of five separate bills passed by the United States Congress in September 1850 that defused a political confrontation between slave and free states on the status of territories acquired in the Mexican–American War.

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Uncle Tom’s Cabin published (March 20, 1852)

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Uncle Tom’s Cabin published (March 20, 1852)

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Published in two volumes in 1852, the novel had a profound effect on attitudes toward African Americans and slavery in the U.S., and is said to have "helped lay the groundwork for the American Civil War."

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Republican Party Formed (March 20, 1854)

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Republican Party Formed (March 20, 1854)

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The GOP was founded in 1854 by opponents of the Kansas–Nebraska Act, which allowed for the potential expansion of chattel slavery into the western territories.

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Signed into law on May 30, 1854, by President Franklin Pierce, was closely related to national and sectional politics in the 1850s.

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The Beating of Charles Sumner, or the Brooks–Sumner Affair, occurred on May 22, 1856, in the United States Senate chamber, when Representative Preston Brooks, a pro-slavery Democrat from South Carolina, used a walking cane to attack Senator Charles Sumner, an abolitionist Republican from Massachusetts.

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The Dred Scott decision was the U.S. Supreme Court’s ruling on March 6, 1857, that having lived in a free state and territory did not entitle an enslaved person, Dred Scott, to his freedom.

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John Brown’s Raid (October 16, 1859-October 18, 1859)

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John Brown’s Raid (October 16, 1859-October 18, 1859)

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John Brown's raid on Harpers Ferry was an effort by abolitionist John Brown, from October 16 to 18, 1859, to initiate a slave revolt in Southern states by taking over the United States arsenal at Harpers Ferry, Virginia.

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Lincoln elected President (November 6, 1860)

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Lincoln elected President (November 6, 1860)

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On November 6, 1860, voters in the United States went to the polls in an election that ended with Abraham Lincoln as President, in an act that led to the Civil War.

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South Carolina secedes (December 20, 1860)

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South Carolina secedes (December 20, 1860)

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South Carolina was the first state to secede from the Union in December 1860, and was one of the founding member states of the Confederacy in February 1861.