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I was running outside when my hand was punctured by a rusty nail. The rusty nail had the pathogen Clostridium tetani living on it. The pathogen entered my body.

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It detects there has been an injury and notifies the body to send out the proper hormones, proteins, and blood cells to fight off infection and heal the wound.

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They are proteins and they are produced to act as a chemical messenger to regulate the immune response.

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The first line of defense was broken through when the nail cut the skin barrier. The pathogen no longer had to fight the molecules like sweat on the skin. In addition, the skin is a protective layer consisting of many layers of epithelial cells.

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The inflammation response began after the penetration of the nail through the skin barrier. Calor, Rubor, Dalor, and Tumor are all signs of inflammation. As you can see in the image these are all the occurrences going on during inflammation.

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They regulate the migration of lymphocytes and activated cells.

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Calor begins which is heat. The wound begins to rise in temperature to try and kill off the invading pathogens.

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Pain begins as the wound burns from being open to all the pathogens and air.

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The area begins to turn red due to the increase in temperature and increase in blood flow to the area. The increase in blood flow is due to the need for leukocytes and other molecules in blood that are need to fight off infection.

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The blood vessels widen and allow them to relax making them more open. That is what causes the increase in blood flow.

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Blood cells flow through the capillaries to get to areas of injury. They contain lymphocytes that will help fight off the infection.

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Type of white blood cell that is getting sent to the site of the wound that helps heal damaged tissues and fight off infection.

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Swelling begins due to the build up of cells and the amount of dead cells that begin to build up due to the process of phagocytosis.

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Macrophages begin to go around in the wound due to the inflammatory response and consume the foreign invaders through phagocytosis. Monocytes make up the macrophages.

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A loss of function begins as a fifth sign of the inflammatory response.

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I began to get a fever which tried to kill off all of the pathogens and foreign invadors.

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I began to rest, ice, compress, and elevate my hand. This helps to get the swelling down.