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The word sleep in the Shakespeare play Macbeth, it was used as a metaphor for innocence and clear mind. When Macbeth murdered Duncan in his sleep, Macbeth´s mind was not clear, and voices haunted him for takings once life.

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¨The innocent sleep, that knits up the raveled sleeve of care, the death of each days life, sore labors bath, balm of hurt minds, great natures second course¨

Sleep is helpful, and is very relaxing while Macbeth can´t enjoy his sleep  because he killed Duncan

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¨Sleep no more, Macbeth does murder sleep¨

This was said after Macbeth killed Duncan, and had nightmares and slept-walked

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¨Macbeth has murder sleep, therefore Macbeth will sleep no more.¨

Macbeth will be no longer at peace because of the guilt of killing King Duncan

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¨You lack the season of all natures, sleep.¨

In this context, Lady Macbeth said to Macbeth that he lacked innocence and peace with the murder of Duncan

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¨Glamis hath murdered sleep¨

Sleep is peaceful, and innocent. But Macbeth´s innocence has been taken away by his actions