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Sectionalism is defined by the growing contrasts between the North and South social, political, and economic values. As new issues arose in an ever-expanding nation, these sectional conflicts worked to divide the country further.

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This legislation admitted Missouri as a slave state and Maine as a non-slave state at the same time, so as not to upset the balance between slave and free states in the nation. It also outlawed slavery above the 36 º 30' latitude line in the remainder of the Louisiana Territory.

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The tariff sought to protect northern and western agricultural products from competition with foreign imports, but the tax would raise the cost of living in the South and cut into the profits of New England's industrialists.

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The Compromise of 1850 amended the Fugitive Slave Act, abolished the slave trade in Washington, D.C., and created California as a free state and Utah as a territorial government.

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Uncle Tom's Cabin is an anti-slavery novel by Harriet Beecher Stowe, published in two volumes in 1852. It had a profound effect on attitudes towards African Americans and slavery in the US, and is said to have helped lay the groundwork for the American Civil War.

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The Republican Party emerged in 1854 to combat the expansion of slavery in American territories.  The Southern Democrats did not approve of the party's politics, and upon selecting their first candidate for the presidential running in 1856, they threatened to secede from the Union.

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Bleeding Kansas was a period of violent warfare between pro-slavery and anti-slavery forces following the creation of the new territory of Kansas in 1854. 55 people were killed between 1855 and 1859, intensifying the ongoing debate over the future of slavery in the US and leading to the Civil War.

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The Dred Scott case, also known as Dred Scott v. Sandford, was a decade-long fight for freedom by a Black enslaved man named Dred Scott. In 1857, the U.S. Supreme Court ruled that living in a free state and territory did not entitle Dred Scott to his freedom. This decision outraged Abolitionists.

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John Brown and his supporters left their farmhouse hide-out to Harpers Ferry on October 16, 1859, where they captured prominent citizens and seized the federal armory and arsenal.

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When Lincoln was elected, many Southerners were angry because they believed he would try to end slavery. Shortly after Lincoln's election, Southern states began to secede, forming the Confederate States of America. This is how the Civil War began.

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The secession of South Carolina was followed by the secession of six more states and the threat of secession by four more states, forming the Confederate States of America.