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REODIQUE, ANDREA J. - M5 DRUG STUDY - BSN 3D

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“As an Angelenean who lives by the core values of pagiging mabuti, magaling at may malasakit sa kapwa, I hereby commit that I complete my academic work with integrity. This means that I shall accomplish my academic work without receiving or giving unauthorized assistance. My work also observes scholarly and intellectual standards, rules on proper citation of sources, and appropriate collection and use of data.”

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Ppd’s Nursing Drug Guide (2008). Aspirin. Retrieved on September 16, 2021, pp. 5

Ppd’s Nursing Drug Guide (2008). Amlodipine. Retrieved on September 16, 2021, pp. 254

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Decreased pain

Absences of MI

Absence of transient ischemic attacks, thrombosis

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Instruct patient to drink aspirin after a meal

Instruct patient not to exceed the recommended dosage, because of the danger of acute poisoning.

Instruct patient to take water and sit upright for 30 mins. To facilitate passing into the stomach

Advise patient of the possibility for allergic reactions in patients with other allergies, nasal polyps, and asthma.

Instruct patient to report tinnitus, confusion, diarrhea, sweating, hyperventilation, visual changes, and bleeding.

Advise patient to read the label of other OTC drugs that may contain aspirin or salicylates

Advise patient to avoid alcohol ingestion: GI bleeding may occur.

Teach patient to recognize and report any symptoms of:

- Hepatotoxicity: dark urine, clay-colored stools, yellow skin, and sclerae
- Renal toxicity: decreased urine output
- Ototoxicity: tinnitus, ringing, roaring in ears, and allergic reactions like rashes and urticaria
-Bleeding

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Administer to patient crushes or whole; chewable tablets may be chewed.

Do not crush enteric product

Give food or milk to decrease gastric irritation

Give antacids 1-2 hrs after enteric products

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Assess pain: Character, Location, Intensity

Identify prior drug history

Assess for allergic reactions: rash, urticaria; the severe allergic reaction may occur in patients with asthma

Assess for ototoxicity: tinnitus, ringing, roaring in ears

Assess for visual changes: blurring halos

Monitor liver function/hepatotoxicity: Dark urine, clay-colored stools, yellow skin, and sclera.

Monitor:

- Renal function: Input-output ratio, BUN
- Blood studies: CBC, HCT, HBG

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ASSESSMENT
PLANNING
IMPLEMENTATION
EVALUATION

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EENT: Dizziness, tinnitus

GI: Nausea, dyspepsia, heartburn, bleeding

Hematology: Increased bleeding, anemia, decreased iron concentration

Others: Hypersensitivity reactions may include urticaria, hives, rashes, angioedema, and anaphylactic shock

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Stomach upset, Headache, Hot flushes

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● Hypersensitivity to salicylates or NSAIDs
● Hemophilia
● Bleeding ulcers
● Hemorrhagic states
● Pregnant women in the third trimester

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● Treatment of mild-to-moderate pain
● Fever
● Various inflammation conditions
● Reduction of risk of death or MI in patients with previous infarction or unstable angina pectoris or recurrent transient ischemia attacks
● Stroke in men who have had transient brain ischemia caused by platelet emboli

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Relieves pain and reduces inflammation by inhibition of peripheral prostaglandin synthesis. It also inhibits the synthesis or action of other mediators of inflammation. It acts on the hypothalamic heat-regulating center to relieve fever, by promoting sweating and vasodilation, leading to heat loss and cooling by evaporation. Also decreases platelet aggregation by preventing the formation of thromboxane A, a platelet aggregating substance.

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Nonsteroidal anti-inflammatory drugs (NSAIDs)

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● Adult:

Route: P.O

Dose: 325-650mg q4 hrs as needed; 500mg q3 hrs as needed; 1000mg q6 hrs as needed.

● Transient ischemic attacks

Route: P.O

Dose: 1300 mg/day in 2-4 doses

● Myocardial infarction prophylaxis:

Route: P.O

Dose: 160-135 mg/day

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Aspilets, Aspilets-EC, Anadol, Astrix, Bayer Aspirin, Cor-30, Cortal, Drugmaker’s Biotech Aspirin

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Acetylsalicylic acid

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Decreased Anginal Pain and BP

Increased exercise tolerance

Patient and family state understanding of the drug therapy

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Teach patient to use as directed even if feeling better; may be taken with other cardiovascular drugs (nitrate, beta-blockers), food helps decrease stomach upset.

Advise Patient to avoid hazardous activities until stabilized on drug and dizziness is no longer a problem. Report symptoms of chest pain, swelling of extremities, irregular pulse, altered vision, shortness of breath, or hypotension.

Advise Patient to comply in all areas of medical regimen: diet, exercise, stress reduction, smoking cessation, and drug therapy.

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Give once a day, without regard to meals.

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Assess cardiorespiratory status: anginal pain, BP, pulse, respiration, ECG

Assess hydration and fluid volume status: input and output ratio, presence of edema, distended neck veins, lung crackles, adequate pulses, and skin turgor

Monitor liver function: ALT, AST, bilirubin

Monitor if platelet count is <150,000/mm^3

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ASSESSMENT
PLANNING
IMPLEMENTATION
EVALUATION

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Palpitations, Peripheral edema, Syncope, Tachycardia, Bradycardia, Arrhythmias, Ventricular asystoles, Dermatitis, Rash, Pruritis, Urticaria, Nausea, Abdominal discomfort, Cramps, Dyspepsia, Shortness of breath, Dyspnea, Wheezing, Muscle cramps, pain or inflammation

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Lightheadedness, Headache, Dizziness Fatigue, Lethargy, Somnolence, Flushing, Sexual difficulties

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● Sick sinus syndrome
● Second or third-degree atrioventricular block, except with functioning pacemaker

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● Hypertension
● Chronic stable angina
● Vasospastic (prinzmetal or variant) angina

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Inhibits influx of calcium ion across cell membranes to produce relaxation of coronary vascular smooth muscle (dilation of coronary arteries), decrease peripheral vascular resistance of smooth muscle (decrease blood pressure), and increases myocardial oxygen delivery in patients with vasospastic angina.

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Calcium Channel Blocker

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● Hypertension and angina:

Route: P.O

Dose: 5mg once a daily, may be increased to a maximum of 10mg

● Chronic Heart failure:

Route: P.O

Dose: 10mg once daily

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● Norvasc, Amcal, Amvasc, Lopicard, Pharex Amlodipine besylate

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● Amlodipine