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Macbeth is made aware that he was deemed the new Thane of Cawdor following the execution of the previous Thane. This makes 2 out of the 3 prophecies told to Macbeth by the witches true, he begins to question what would happen if the 3rd, being crowned king were to be true. "If chance will have me, king, why, chance may crown me without my stir" (Act 1, Scene 3)  Macbeth begins to plan the path to being crowned king, and his obstacles, King Duncan and his sons must be taken out of the way. Macbeth is fighting with himself if he can take that step toward the crown.

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After receiving word from Macbeth that there is a chance that they could take hold of the crown, Lady Macbeth prepares herself to take charge. "Come, you spirits that tend on mortal thoughts, unsex me here, and fill me from the crown to the toe top-full of direst cruelty! Make thick my blood;" (Act 1, Scene 5) Lady Macbeth wishes away her femininity and weakness to gain strength. She plans to use this strength and masculinity to do away with King Duncan and secure Macbeth's place as the new king.

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Macbeth murders King Duncan in his sleep, he returns to Lady Macbeth with bloodied hands and daggers. All his work to rid his hands of the King's blood is unsuccessful. "Will all great Neptune's ocean wash this blood clean from my hand?"(Act 2, Scene 2) In a panic, Macbeth vigorously washes the blood from his hands, however, every drop of water that comes into contact, shifts to blood as well, dirtying him and his surroundings. All he can see is what represents his terrible sin committed for greed and power. 

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Macbeth returns after murdering King Duncan with the weapons used to do the deed. Horrible mistake, Lady Macbeth, calm and collected takes over to fix what Macbeth has done and leaves no evidence. "Give me the daggers. The sleeping and the dead. Are but as pictures. 'Tis the eye of childhood. That fears a painted devil. If he bleeds, Ill gild the faces of the grooms withal, for it must seem their guilt." (Act 2, Scene 2) Lady Macbeth is seen as stable and sure of the plan ahead. She is Macbeth's rock and in his fault, she takes charge of fixing the situation, she isn't affected mentally by the murders.

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Banquo grows untrusting of Macbeth and his actions to take power in Scotland. With the knowledge of Banquo's prophecy to father future kings, Macbeth sends to end his lineage to keep his power. "That I require clearness: and with him to leave no rubs nor botches in the work Fleance his son, that keeps him company, whos absence is no less material to me than his father's must embrace the fate of that dark hour."(Act 3, Scene 1) Macbeth is sick, barren, and broken inside. Banquo, once his close companion, is flourishing with life and promise for his future descendants. They sprouted from the same origin but branched into horribly different endings. 

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Lady Macbeth begins to believe that killing isn't worth the power, the actions committed by the couple are unable to be reversed and they are now living in their nightmare. "How now my lord, why do you keep alone, of sorriest fancies your companions making,using those thoughts which should indeed have died with them they think on? Things without all remedy should be without regard. What's done is done."(Act 3, Scene 2) Lady Macbeth is haunted by the lives that have been taken. Her mind is filled with what Macbeth is hiding from her and her heart cannot take the secrets, lying, and betrayal anymore. 

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Macbeth receives messages from three apparitions, beware, Macbeth, no person born of a woman can kill you and you shall not vanquish until the wood moves up the hill to Dunsinane. As a way to punish Macduff, Macbeth sends two assassins to Fife to murder the Macduff family. "The castle of Macduff I will surprise; seize upon Fife; give to the edge o' the sword his wife his babes, and all the unfortunate souls"(Act 4, Scene 1) Murder has clouded Macbeth's mind, the line between right and wrong has been completely blurred as he sends to kill the innocent.

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Lady Macbeth is absent throughout all of Act 4. Her absence represents the growth of her mental torment and regret as she is haunted by the actions she and her partner took to strengthen their power. After Macbeth's measures to silence Banquo, Lady Macbeth is hidden away, trapped in her guilt and remorse. Her lack of presence during Macbeth's decisions against Macduff proves that she is no longer a vital decision-maker and her power has almost disappeared. 

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Macbeth is made aware of his wife's suicide and has a small unremarkable reaction. "There would have been a time for such a word. Tomorrow and tomorrow and tomorrow creeps in this petty pace from day to day"(Act 5, Scene 5) Macbeth has grown so desensitized to death. He is so trapped in his mind and past deeds that he can only look out for himself. He is numb to feeling and there is no difference between life and death. To the news of his wife's death, he can only express that it would have been better if she had done so at a later time. 

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Lady Macbeth is living through her most traumatic moments in a mental break. She regresses to the night where it began, Duncan's death."To bed, to bed; there's knocking at the gate. Come, come, come, come, give me your hand. What's done cannot be undone. - To bed, to bed, to bed."(Act 5, Scene 1) This is the last scene that Lady Macbeth is seen in before she commits suicide. She had grown so hurt, tormented, and regretful by her actions that led to a horrible line of murder, lying, and betrayal that she could only heal by going to bed, and ending her life.