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Padlet untuk kelas cikgu telah diupgrade:

1. Padlet untuk mendapatkan nota, link video, bahan-bahan dan jawapan modul Sains:
https://padlet.com/khairulhazmansmkap/92v5wlufrkanrr25

2. Padlet untuk menghantar, mengumpulkan dan memaparkan hasil kerja Sains murid-murid 4AB
https://padlet.com/KhairulhazmanMOE/hasilkerja4AB

Untuk masuk dan akses, murid-murid mesti guna akaun MOE. Jika belum boleh masuk, sila check email jemputan dalam gmail MOE.

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 Variasi Selanjar dan Variasi Tak Selanjar

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 Variasi Selanjar dan Variasi Tak Selanjar

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Sains Tingkatan 4 KSSM I BAB 5 I Variasi Selanjar dan Variasi Tak Selanjar

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SAINS TINGKATAN 4 KSSM I Aktiviti Penentuan Jenis Variasi

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PEWARISAN PENYAKIT GEN DAN KAEDAH MENGESAN PENYAKIT GEN

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PEWARISAN PENYAKIT GEN DAN KAEDAH MENGESAN PENYAKIT GEN

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5.3 PEWARISAN PENYAKIT GEN DAN KAEDAH MENGESAN PENYAKIT GEN | SAINS T4

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5.3 APLIKASI PENYELIDIKAN GENETIK | SAINS T4

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5.4 TEKNOLOGI KEJURUTERAAN GENETIK | SAINS T4

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ANIMAL PHARM - INSIDE GMO TRANSGENICS AND CLONING

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ANIMAL PHARM - INSIDE GMO TRANSGENICS AND CLONING

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ANIMAL PHARM - INSIDE GMO TRANSGENICS AND CLONING

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What is a GMO? Let us quickly explain...

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http://honeymash.com for more... What is a GMO? Its simply a Genetically Modified Organism. For example if a cotton seed plant has its DNA modified to protect it from hash growing climates, that it has been modified at the DNA level and is a Genetically Modified Organism.

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18 Genetically Modified Organisms You Don't Know About

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18 Genetically Modified Organisms You Don't Know About

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18 Genetically Modified Organisms You Don't Know About

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Monster leech swallows giant worm - Wonders of the Monsoon: Episode 4 - BBC Two

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The diabolical ironclad beetle ( Phloeodes diabolicus) of North America doesn't have the visual pizzazz of some of its more shiny beetle cousins, looking more like a small piece of gnarly bark or stone.

But what it lacks in dazzle, it makes up for in durability: its exoskeleton is one of the toughest materials in the natural world. Now scientists might have finally figured out its secrets - and are starting to apply them to new materials.

Not only is it incredibly difficult for predators to attack, the diabolical ironclad beetle has been known to survive not just human stompings, but being run over by cars. So tough is its exoskeleton, entomologists have found it challenging to mount the beetle for display using steel pins.

Even though it can't fly, the bug's survival skills are through the roof. And scientists have just used a suite of tools to discover the physical and mechanical properties that give the diabolical ironclad beetle its incredible fortitude.

"The ironclad is a terrestrial beetle, so it's not lightweight and fast but built more like a little tank," said materials scientist David Kisailus of the University of California Irvine.

"That's its adaptation: It can't fly away, so it just stays put and lets its specially designed armour take the abuse until the predator gives up."

The little beetle measures just over a centimetre in length, and spends its time crawling around the southwest deserts of North America, lurking under rocks, or under the bark of trees. The team collected their beetles from the Inland Empire region of California.

First, they conducted steel plate compression tests of the entire exoskeleton to ascertain just how much force the beetle could withstand, comparing the results to other beetle species from the same region with similar predators, such as pecking birds, and the same defence strategy, playing dead.

The similar beetles were able to withstand an average peak load of less than 68 Newtons. The diabolical ironclad beetle, by contrast, could withstand a maximum force of 149 Newtons - that's a jaw-dropping 39,000 times its own body weight.

Just imagine the weight of having 39,000 clones piled on top of you. Yikes.

Anyway, the next step was trying to figure out how the little beetle does what it does, for which the team employed spectroscopy, scanning electron microscopy and CT scans to closely study the hard shell.

They also conducted simulations and used 3D printed models to verify their findings.

The architecture and material composition of the entire exoskeleton accounts for some of the toughness; but the key, the researchers found, lay in the elytra.

In flying beetles, the elytra are the hard forewings that act as wing cases to protect the more delicate veined hindwings that the insect uses for flight.

Because the diabolical ironclad beetle doesn't fly, its elytra have hardened even further and become locked together along a suture line to act more like armour.

This exoskeleton, the team found, is composed of chitin, a fibrous material derived from glucose, and a protein matrix. When they compared the diabolical ironclad beetle's exoskeleton to that of a similar beetle, they found that the ironclad had significantly more protein - about 10 percent more by weight.

But the suture line along which the beetle's elytra are fused ended up playing a crucial role in its toughness.

"The suture kind of acts like a jigsaw puzzle," said materials scientist Pablo Zavattieri of Purdue University. "It connects various exoskeletal blades - puzzle pieces - in the abdomen under the elytra."

When the team looked closer to observe how these interlocking structures performed under pressure, they found something interesting.

Rather than snap apart, as you'd expect puzzle pieces to do, the microstructures within the exoskeletal blades gave way to layered parallel fracturing, a process known as delamination.

This is aided by a coating of microscopic hairs called microtrichia on the outside surfaces of the blades that increase friction, preventing the interlocking edges from slipping apart. This combination of features allows the elytra to deform more gently, which dissipates energy more evenly and prevents the exoskeleton from snapping and killing the insect.

"When you break a puzzle piece, you expect it to separate at the neck, the thinnest part," Kisailus said. "But we don't see that sort of catastrophic split with this species of beetle. Instead, it delaminates, providing for a more graceful failure of the structure."

This discovery could pave the way for the development of more durable materials to overcome engineering challenges. This could lead, for example, to safer aircraft engines, which employ fasteners that add structural stress that decrease the durability of the overall engine.

The researchers built an aircraft engine fastener using carbon fibre material and mimicking the jigsaw-puzzle structure of the diabolical ironclad beetle's suture.

After conducting loading tests, they found that their fastener was just as strong as the fasteners currently in use, but significantly tougher.

"An active engineering challenge is joining together different materials without limiting their ability to support loads," said mechanical engineer David Restrepo of the University of Texas at San Antonio.

"The diabolical ironclad beetle has strategies to circumvent these limitations."

The research has been published in .

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This Beetle's Shell Is So Diabolically Tough It Can Be Driven Over. Now We Know How

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The diabolical ironclad beetle ( Phloeodes diabolicus) of North America doesn't have the visual pizzazz of some of its more shiny beetle cousins, looking more like a small piece of gnarly bark or stone. But what it lacks in dazzle, it makes up for in durability: its exoskeleton is one of the toughest materials in the natural world.

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DNA: Coding yang Mampu Menyimpan Berjuta Gigabyte

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SAINS - TINGKATAN 4 | 6.0 - SOKONGAN PERGERAKAN DAN PERTUMBUHAN (SIRI 1)

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trait - ciri lesung pipit merupakan ciri resesif yang terdapat pada manusia

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Apa Itu Meiosis? Dan Apa Kepentingan Proses Ini Untuk Kita?

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Giant Coconut Crab – the largest land crab in the world

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BIOLOGI Tingkatan 4 SPM - Pembahagian Sel Meiosis

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Sains Tingkatan 4 KSSM I BAB 5 I Apakah Kromosom,Gen dan DNA ???

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Sains Tingkatan 4 KSSM I BAB 5 I Mekanisme Pewarisan Mendel

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CARA SENANG!!! : Bagaimana Jantina Lelaki dan Perempuan Ditentukan?

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Sains Tingkatan 4 KSSM I BAB 5 I Pewarisan : Maksud Gen dan Alel

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Sains Tingkatan 4 KSSM I BAB 5 I Mutasi Kromosom dan Mutasi Gen

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Sains Tingkatan 4 KSSM I BAB 6 I Jenis Sistem Sokongan Haiwan

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Assalammualaikum semua anak murid cikgu yang dikasihi. Bermulalah sesi PDPR bagi kelas kita di alam maya. Kali ini cikgu gunakan padlet bagi memudahkan untuk kamu akses bahan-bahan.

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Selamat datang pelajar kelas 4AB..!

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Japanese Street Food - $600 GIANT RAINBOW LOBSTER Sashimi Japan Seafood

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📓Nota BUKU DIGITAL
Sains f4 KSSM BAB 1-12
💋Set lengkap🥰

🥼Bab 1 Langkah Keselamatan di dalam Makmal
https://online.fliphtml5.com/rtmqr/qntk/

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Semoga bermanfaat 🌷

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Sains Tingkatan 4 KSSM I BAB 6 I Jenis dan Fungsi Rangka Dalam

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See a Salamander Grow From a Single Cell in this Incredible Time-lapse | Short Film Showcase

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Beberapa istilah yang perlu difahami
Kromosom
Gen
DNA
Kariotip
Haploid
Diploid
Sel soma
Kromosom seks
Kromosom autosom
Kiasma
Sinapsis
Pindah Silang
Bivalen

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Missing an X: Turner Syndrome campaign video

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Some humans and animals are albino, but why? What causes this disorder, and how common is it? Is Homeopathy Real Science? https://www.youtube.com/watch?v=1LFp6ASW0Ao Read More: Albinism http://www.mayoclinic.org/diseases-conditions/albinism/basics/causes/con-20029935 "Albinism is caused by a mutation in one of several genes. Each of these genes provides instructions for making one of several proteins involved in the production of melanin."

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6.1 Sokongan, pergerakan dan Pertumbuhan Haiwan

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Bagaimana Cacing Tanah Bergerak? Apa Fungsi Rangka Hidrostatik?

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Eksperimen Yang Sesuai Untuk Uji Kekuatan Tulang Berongga dan Tulang Padat

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Sains Tingkatan 4 KSSM I BAB 6 I Lengkung Pertumbuhan dan Ekdisis

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Sains Tingkatan 4 KSSM I BAB 6 I SISTEM RANGKA MANUSIA

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Sains Tingkatan 4 KSSM I BAB 6 I Sistem Sokongan & Kestabilan Haiwan

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Ruangan ini akan menampilkan video-video eksperimen bagi ulangkaji memandangkan ramai yag lemah bahagian eksperimen

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Gene Therapy Partially Restores Vision in Blind Patient in First Case of Its Kind

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Gene Therapy Partially Restores Vision in Blind Patient in First Case of Its Kind

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A blind man who lost his sight to a neurodegenerative eye disease decades ago has had his vision partially restored

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A blind man who lost his sight to a neurodegenerative eye disease decades ago has had his vision partially restored, thanks to a first-of-its-kind experimental gene therapy.

The patient in question, a 58-year-old male, was diagnosed 40 years ago with retinitis pigmentosa: a progressive, inherited group of genetic disorders that leads to loss of vision due to mutations that cause light-sensitive photoreceptor cells in the retina to break down.

Retinitis pigmentosa (RP) is generally considered a rare disorder, with estimates suggesting only one in 4,000 people have the condition, but it's nonetheless thought to affect approximately 2 million people worldwide.

For those people and their families, recent advancements in optogenetics could be a source of new hope for restored vision - although it's worth emphasizing this approach is still very much in the experimental stage, with practical treatments likely to be years away.

In the 58-year-old patient in question, degradation in his sight due to RP meant his visual acuity was limited to light perception: He could still perceive the presence of light and differentiate it from darkness, but couldn't make out anything else.

At least, not without assistance. As part of the PIONEER clinical trial, the man was actually able to partially see again with one of his eyes, due to a combination of gene therapy and pulses of light stimulating the eye, courtesy of special goggles.

The technique is called optogenetic vision restoration, although this represents the first time it's been used to deliver partial functional recovery in a neurodegenerative disease, the researchers say.

"We present the first evidence that injection of an optogenetic sensor-expressing gene therapy vector combined with the wearing of light-stimulating goggles can partially restore visual function in a patient with RP who had a visual acuity of only light perception," the team, led by ophthalmologist José-Alain Sahel from the University of Pittsburgh, explains in a new paper.

In the study, the man was given an intravitreal injection in his worst-seeing eye, delivering an adeno-associated virus - a form of gene therapy where the viral vector infects human tissue with a beneficial payload.

Here, the virus administered a combination of light-sensitive proteins, designed to boost light perception function in the man's damaged retina cells.

In conjunction with the special goggles - which stimulated his eye with bursts of light that corresponded to the shape and position of objects in front of him - the man was able to partially see once more.

"The light-stimulating goggles capture images from the visual world using a neuromorphic camera that detects changes in intensity, pixel by pixel, as distinct events," the researchers explain.

"The goggles then transform the events into monochromatic images and project them in real time as local 595-nm light pulses onto the retina."

With the aid of this experimental setup, the patient - who was previously unable to visually detect anything in front of him - was able to successfully perceive, locate, and touch various objects that had been placed on a table in front of him, including a notebook, a staple box, and a tumbler.

"The visual process leading to the percept was effective enough to enable the patient to orient toward the object and perform the visuomotor task of reaching for it," the researchers explain.

At the same time, the man wore a non-invasive electroencephalographic (EEG) cap, designed to provide a readout of neuronal activity across the cortex during the experiment, providing another measure of the man's partially restored vision.

"The EEG recordings suggested that retinal activity evoked by the optogenetic stimulation of the retina propagates to the primary visual cortex and modulates its activity," the authors write.

"This cortical activity, quantified as changes in amplitude of the local EEG alpha power, conveys sufficient information to allow object versus no-object stimulations to be decoded on a single-trial basis."

While there's a lot more research to be done before this kind of therapy can be administered to regular patients, the signs here are very promising, giving hope that optogenetic treatments using light-stimulation optic devices could one day restore at least some level of vision for blind patients with retinitis pigmentosa.

In one test, the man was also able to identify and count the number of white stripes on the crosswalk outside of the laboratory. When wearing the goggles after the tests, he reported being able to see other objects outside of the lab.

"Subsequently, the patient testified to a major improvement in daily visual activities, such as detecting a plate, mug or phone, finding a piece of furniture in a room or detecting a door in a corridor but only when using the goggles," the researchers write.

"Thus, treatment by the combination of an optogenetic vector with light-stimulating goggles led to a level of visual recovery in this patient that was likely to be of meaningful benefit in daily life."

The findings are reported in Nature Medicine.

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Gene Therapy Partially Restores Vision in Blind Patient in First Case of Its Kind

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A blind man who lost his sight to a neurodegenerative eye disease decades ago has had his vision partially restored, thanks to a first-of-its-kind experimental gene therapy. The patient in question, a 58-year-old male, was diagnosed 40 years ago with retinitis pigmentosa: a progressive, inherited group of genetic disorders that leads to loss of vision due to mutations that cause light-sensitive photoreceptor cells in the retina to break down.

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Nuclear power is often promoted as one of the best ways to reduce our reliance on fossil fuels to generate the electricity we need, but new research suggests that going all-in on renewables such as wind and solar might be a better approach to seriously reducing the levels of carbon dioxide in the atmosphere.

Based on an analysis of 123 countries over a quarter of a century, the adoption of nuclear power did not achieve the significant reduction in national carbon emissions that renewables did - and in some developing nations, nuclear programmes actually pushed carbon emissions higher.

The study also finds that nuclear power and renewable power don't mix well when they're tried together: they tend to crowd each other out, locking in energy infrastructure that's specific to their mode of power production.

Given nuclear isn't exactly zero carbon, it risks setting nations on a path of relatively higher emissions than if they went straight to renewables.

However, it's too early to rush to a judgement on nuclear just yet.

It's important to note that the study looked specifically at data from 1999-2014, so it excludes more recent innovations in nuclear power and renewables, and the scientists themselves say they have found a correlation, rather than cause and effect. But it's an interesting trend that needs further investigation.

"The evidence clearly points to nuclear being the least effective of the two broad carbon emissions abatement strategies, and coupled with its tendency not to co-exist well with its renewable alternative, this raises serious doubts about the wisdom of prioritising investment in nuclear over renewable energy," says Benjamin Sovacool, a professor of energy policy at the University of Sussex in the UK.

"Countries planning large-scale investments in new nuclear power are risking suppression of greater climate benefits from alternative renewable energy investments."

The researchers suggest the tighter regulations and longer lead times associated with nuclear power are responsible for some of the statistics explored here, while the large-scale development that nuclear requires tends to leave less room for renewable projects that work on a smaller scale.

There are also broader considerations to weigh up - nuclear and renewables will be two factors among many in the policies put together by governments when it comes to reducing carbon emissions.

Plus, given the time frame, a lot of the nuclear power plants covered by this study are likely to have been getting towards the end of their lifespans, which means more energy is required to maintain them.

Whatever the ins and outs of the nuclear policies, the study does show a clear link between greater adoption of renewable projects and lower carbon emissions overall.

The study authors propose that by cutting out nuclear altogether, these renewable gains could be even greater.

"This paper exposes the irrationality of arguing for nuclear investment based on a 'do everything' argument," says researcher for technology policy Andrew Stirling at the University of Sussex.

"Our findings show not only that nuclear investments around the world tend on balance to be less effective than renewable investments at carbon emissions mitigation, but that tensions between these two strategies can further erode the effectiveness of averting climate disruption."

It's a more contentious issue than you might think.

Many scientists (and Bill Gates) say that nuclear energy is our only option at this point, maintaining a view that it can replace fossil fuels with efficiencies that renewables can't match right now.

A study from 2018 also concluded that nuclear power has to be an essential part of the mix if we're going to reduce the temperature of the planet by as much as we need to - at least until options like wind and solar have had time to scale up.

Work continues to make nuclear a leaner, more agile source of energy that can better operate alongside renewable projects, which will help it improve on the figures in this study.

In the meantime, the study authors are asking for more detailed reports from the nuclear industry, in order to better understand its benefits.

"While it is important to acknowledge the correlative nature of our data analysis, it is astonishing how clear and consistent the results are across different time frames and country sets," says Patrick Schmid, from the ISM International School of Management in Germany.

"In certain large country samples the relationship between renewable electricity and CO2-emissions is up to seven times stronger than the corresponding relationship for nuclear."

The research has been published in Nature Energy.

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25-Year Study of Nuclear vs Renewables Says One Is Clearly Better at Cutting Emissions

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Nuclear power is often promoted as one of the best ways to reduce our reliance on fossil fuels to generate the electricity we need, but new research suggests that going all-in on renewables such as wind and solar might be a better approach to serious

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In October 1961, the Soviet Union dropped the most powerful nuclear bomb in history over a remote island north of the Arctic Circle.

Though the bomb detonated nearly 2.5 miles (4 kilometers) above ground, the resulting shockwave stripped the island as bare and flat as a skating rink.

Onlookers saw the flash more than 600 miles (965 km) away, and felt its incredible heat within 160 miles (250 km) of Ground Zero. The bomb's gargantuan mushroom cloud climbed to just below the edge of space.

This was RDS-220 - also known as the Tsar Bomba. Nearly 60 years after the bomb's record-shattering detonation, no single explosive device has come close to matching its destructive power.

Last week, Rosatom State Atomic Energy Corporation (Russia's state atomic agency) released 40 minutes of previously classified footage, showing the bomb's journey from manufacture to mushroom cloud. Now, you can watch it all on YouTube. (The countdown to detonation begins at 22:20).

Soviet Premier Nikita Khrushchev personally commissioned the construction of the Tsar Bomba in July 1961, Popular Mechanics reported. While Krushchev wanted a 100-megaton nuclear weapon, engineers ultimately presented him with a 50-megaton version - equivalent to 50 million tons (45 million metric tons) of TNT detonated at once.

Even with half of the premier's requested payload, the bomb was unfathomably powerful. The bomb was thousands of times stronger than the nukes detonated by the United States over Hiroshima and Nagasaki during World War II, and dwarfed the detonation of Castle Bravo - the most powerful nuclear weapon ever tested by the United States - which yielded just 15 megatons (13 million metric tons).

As the new footage shows, the Tsar Bomba was enormous, weighing 27 tons (24 metric tons) and measuring about as long as a double-decker bus. An aerial bomber carried the massive weapon high over the Novaya Zemlya islands in the Russian Arctic, then dropped it via parachute before clearing the area.

The explosion was so powerful that it actually knocked the aircraft out of the sky, causing the plane to plummet 3,000 feet (900 meters) before the pilot could right it, according to Popular Mechanics.

Thankfully, no human casualties have been attributed to the Tsar Bomba detonation, and no bomb matching its power was ever tested again. In 1963, the United States, the Union of Soviet Socialist Republics (USSR) and the United Kingdom signed the Limited Nuclear Test Ban Treaty, which prohibited airborne nuclear weapons tests.

Since then, atomic tests have carried on underground as nations continue to stockpile nuclear weapons, occasionally changing the geography of the Earth around them.

One 2018 nuclear test conducted in North Korea caused an entire mountain to collapse over the test facility - a reminder, perhaps, that the world hardly needs another Tsar Bomba in order to wreak devastating nuclear damage.
This article was originally published by Live Science. Read the original article here.

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Russia Just Declassified Footage of The Most Powerful Nuclear Bomb Blast in History

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In October 1961, the Soviet Union dropped the most powerful nuclear bomb in history over a remote island north of the Arctic Circle. Though the bomb detonated nearly 2.5 miles (4 kilometers) above ground, the resulting shockwave stripped the island as bare and flat as a skating rink.

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Ekdisis: Belalang Ganti Eksoskeleton (Kerangka Luar) 🦗 Ecdysis of Grasshopper

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Ekdisis: Belalang Ganti Eksoskeleton (Kerangka Luar) 🦗 Ecdysis of Grasshopper

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BELANGKAS MASAK LEMAK CILI PADI || Horseshoe Crab Cooked in Spicy Coconut Sauce

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Boats and boating--Equipment and supplies

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Dr Ian - Chiropractic CHANGES LIFE for teenager with acute PAIN & DEAD LEG

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Chris Leong Consult Special Case Caution don't try this at Home ✅