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Kidney disease is what occurs when your kidneys are damaged due to a number of reasons (liquid intake, diet, etc). This may affect the way your body cleans the blood stream, filter out wastes and  regulate blood pressure. To extremes, this disease can cause kidney failure which may be life threatening.

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Symptoms may include:
- Drowsiness
- Sickness/Headaches
- Urination Problems
- Loss of Appetite

Causes may include:
- Renal Artery Damage
- Uncontrolable Blood Sugar/Pressure
- Side Effect of Medicine
- Excessive Alcohol Intake

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A healthy kidney will process blood efficiently and the epithelial tissue lining the renal tubules will have not been procreated.

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- Cysts full of fluid and epithelial begin to form
- Glucose become Ceramide
- Cells begin to quickly divide and split
- Synthesis of Glucosylceramide begins to increase in cystic cells
- An increase in Apoptosis and Cell Proliferation

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The incorrect mechanisms all contribute to the cysting and changes in the kidney. Some of these mechanisms may be:
- Decreasing cell size, growth and division
- The modification of the differentiation of apoptosis and proliferation
- The promotion of planar cell polarity

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Signal transduction pathways are the correct cell signaling pathways involved in this disease.

The kidney has millions of little units called Nephrons and they all have a glomerulus attached to a tubule. Blood passes through these vessels while extra fluids travel through the tubules. Most fluids are filtered out with the waste being carried out as urine.

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Scientist are currently looking into STEM Cells in kidney research.
- Stem cells are being searched for in the Bowman Capsule of the Nephrons
- Scientist are looking at other cell centers in the kidney such as tubules.
- Scientist are also looking for iPSC (Induced Pluripotent Stem Cells) that has the ability to spread to any cell or tissue
- Scientist are also looking for a treatment to STEM Cells.
- Scientist are also looking into modifying renal cells to avoid failure or disease