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			Biofield Treatment | Properties of 2,4-Dihydroxybenzophenone
		
	

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			Biofield Treatment | Properties of 2,4-Dihydroxybenzophenone
		
	

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Biofield treatment is an alternative approach which may be useful to improve these unfilled space associated with hepatitis infected patients. The human biofields is the energetic matrix that surrounds the human.

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Physical, Thermal and Spectral Properties of Biofield Energy Treated 2,4-Dihydroxybenzophenone | Mahendra Trivedi | Alice Branton | Dahryn Trivedi | Gopal Nayak | Academic Room

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Study background: 2,4-Dihydroxybenzophenone (DHBP) is an organic compound used for the synthesis of pharmaceutical agents. The objective of this study was to investigate the influence of biofield energy treatment on the physical, thermal and spectral properties of DHBP. The study was performed in two groups (control and treated).

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			Biofield Energy Treatment on 2,4-Dihydroxybenzophenone
		
	

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			Biofield Energy Treatment on 2,4-Dihydroxybenzophenone
		
	

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View Mahendra Kumar Trivedi biofield energy treatment on 2,4-Dihydroxybenzophenone . Dihydroxybenzophenone is an organic compound used for the synthesis of pharmaceutical agents.

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Research ArticleOpen Access

Trivedi et al., Clin Pharmacol Biopharm 2015, 4:4

http://dx.doi.org/10.4172/2167-065X.1000145

Volume 4 * Issue 4 * 1000145

ISSN: 2167-065X CPB, an open access journal

Physical, Thermal and Spectral Properties of Biofield Energy Treated

2,4-Dihydroxybenzophenone

Mahendra Kumar Trivedi1, Rama Mohan Tallapragada1 , Alice Branton1 , Dahryn Trivedi1, Gopal Nayak1, Rakesh Kumar Mishra2 and Snehasis

1Trivedi Global Inc., 10624 S Eastern Avenue Suite A-969, Henderson, NV 89052, USA

2Trivedi Science Research Laboratory Pvt. Ltd., Hall-A, Chinar Mega Mall, Chinar Fortune City, Hoshangabad Rd., Bhopal- 462026, Madhya Pradesh, India

Study background: 2,4-Dihydroxybenzophenone (DHBP) is an organic compound used for the synthesis of

pharmaceutical agents. The objective of this study was to investigate the inuence of bioeld energy treatment on the

physical, thermal and spectral properties of DHBP. The study was performed in two groups (control and treated). The

control group remained as untreated, and the treated group received Mr. Trivedi's bioeld energy treatment.

Methods: The control and treated DHBP samples were further characterized by X-ray diffraction (XRD), differential

scanning calorimetry (DSC), thermogravimetric analysis (TGA), laser particle size analyser, surface area analyser,

Fourier transform infrared (FT-IR) spectroscopy, and ultra violet-visible spectroscopy (UV-vis) analysis.

Results: The XRD study indicated a slight decrease in the volume of the unit cell and molecular weight of treated

DHBP as compared to the control sample. However, XRD study revealed an increase in average crystallite size of the

treated DHBP by 32.73% as compared to the control sample. The DSC characterization showed no signicant change in

the melting temperature of treated sample. The latent heat of fusion of the treated DHBP was substantially increased by

11.67% as compared to the control. However, TGA analysis showed a decrease in the maximum thermal decomposition

temperature (Tmax ) of the treated DHBP (257.66ºC) as compared to the control sample (260.93ºC). The particle size

analysis showed a substantial increase in particle size (d50 and d99) of the treated DHBP by 41% and 15.8% as compared

to the control sample. Additionally, the surface area analysis showed a decrease in surface area by 9.5% in the treated

DHBP, which was supported by the particle size results. Nevertheless, FT-IR analysis showed a downward shift of

methyl group stretch (2885→2835 cm-1 ) in the treated sample as compared to the control. The UV analysis showed a

blue shift of absorption peak 323→318 nm in the treated sample (T1) as compared to the control.

Conclusion: Altogether, the results showed signicant changes in the physical, thermal and spectral properties of

treated DHBP as compared to the control.

Keywords: 2,4-Dihydroxybenzophenone; X-ray diraction; ermal

analysis; Laser particle size analyser; Surface area analyser; Fourier

transform infrared spectroscopy; Ultra violet-visible spectroscopy.

Abbreviations: XRD: X-Ray Diraction; DSC: Dierential

Scanning Calorimetry; TGA: ermo Gravimetric Analysis; FTIR:

Fourier Transform Infrared Spectroscopy, UV-Vis: Ultra Violet-

Visible Spectroscopy Analysis; CAM: Complementary and Alternative

Benzophenone an aromatic ketone is an important class of organic

compounds used in perfumes and photochemicals. Benzophenones are

used as an intermediate for the synthesis of dyes, pesticides and drugs

[1]. ese compounds are widely used for the synthesis of various

drugs having anxiolytic, hypnotic and antihistaminic activities [2].

2,4-dihydroxybenzophenone (DHBP) is used as UV-light absorber in

resinous and polymer compositions such as polystyrene, acrylonitrile

polymer and other copolymers [3]. Moreover, these UV light absorbers

are also used in the preparation of sunscreen agents for cosmetic

applications. DHBP has been used as promising sunscreen agent that

reduces the skin damage by blocking the ultra violet light [2].

e chemical and physical stability of the pharmaceutical

compounds are most desired quality attributes that directly aect its

safety, ecacy, and shelf life [4]. Hence, it is required to explore some

new alternate approaches that could alter the physical and chemical

properties of the compounds such as DHBP. Recently bioeld energy

treatment has been used as a plausible approach for physicochemical

modication of metals [5,6], ceramic [7], organic products [8]

and pharmaceutical drugs [9]. erefore, aer considering the

pharmaceutical applications of DHBP authors planned to investigate

the inuence of bioeld energy treatment on physical, spectral and

thermal properties of DHBP.

e National Centre for Complementary and Alternative

Medicine (NCCAM), a part of the National Institute of Health (NIH),

recommends the use of Complementary and Alternative Medicine

(CAM) therapies as an alternative in the healthcare sector, and about

36% of Americans regularly uses some form of CAM [10]. CAM

includes numerous energy-healing therapies; bioeld therapy is one of

the energy medicine used worldwide to improve the health.

Fritz, has rst proposed the law of mass-energy interconversion

and aer that Einstein derived the well-known equation E=mc2 for

light and mass [11,12]. ough, conversion of mass into energy is fully

*Corresponding author: Dr. Snehasis Jana, Trivedi Science Research Laboratory Pvt.

Ltd., Hall-A, Chinar Mega Mall, Chinar Fortune City, Hoshangabad Rd., Bhopal- 462026,

Citation: Trivedi MK, Tallapragada RM, Branton A, Trivedi D, Nayak G, et al.

(2015) Physical, Thermal and Spectral Properties of Bioeld Energy Treated

2,4-Dihydroxybenzophenone. Clin Pharmacol Biopharm 4: 145. doi:10.4172/2167-

the terms of the Creative Commons Attribution License, which permits unrestricted

use, distribution, and reproduction in any medium, provided the original author and

Treated 2,4-Dihydroxybenzophenone. Clin Pharmacol Biopharm 4: 145. doi:10.4172/2167-065X.1000145

Volume 4 * Issue 4 * 1000145

ISSN: 2167-065X CPB, an open access journal

all atoms in a molecule multiplied by the Avogadro number (6.023

×1023 ).e percent change in molecular weight was calculated using

Percent change in molecular weight = [(Mt -Mc)/Mc]×100

powder sample respectively.

Percentage change in average crystallite size was calculated using

treated powder samples respectively.

Dierential scanning calorimetry (DSC)

DSC was used to investigate the melting temperature and latent

heat of fusion (∆H) of samples. e control and treated DHBP samples

were analysed using a Pyris-6 Perkin Elmer DSC at a heating rate of

10ºC/min under air atmosphere and the air was ushed at a ow rate of

5 mL/min. Predetermined amount of sample was kept in an aluminum

pan and closed with a lid. A blank aluminum pan was used as a

reference. e percentage change in latent heat of fusion was calculated

using following equations:

% change in Latent heat of fusion 100

Where, ΔH Control and ΔH Treated are the latent heat of fusion of

control and treated samples, respectively.

ermogravimetric analysis-dierential thermal analysis

e thermal stability of control and treated DHBP were analyzed

by using Mettler Toledo simultaneous TGA and Dierential thermal

analyser (DTA). e samples were heated from room temperature to

400º C with a heating rate of 5ºC/min under air atmosphere.

e average particle size and particle size distribution were

analyzed by using Sympetac Helos-BF Laser Particle Size Analyser with

a detection range of 0.1 to 875 micrometer. Average particle size d50 and

d99 (size exhibited by 99% of powder particles) were computed from

laser diraction data table. e percentage changes in d50 and d99 values

were calculated by the following formula:

Percentage Change in d99 size = 100× (d99 treated- d99 control)/ d99

e surface area of control and treated DHBP were characterized

by surface area analyser, SMART SORB 90 Brunauer-Emmett-Teller

(BET) using ASTM D 5604 method that had a detection range of

0.2-1000 m2 /g. Percent change in surface area was calculated using

% change in surface area 100

Where, S Control and S Treated are the surface area of control and treated

validated, but the inverse of this relation, i.e. energy into mass is not

yet veried scientically. Additionally, it was stated that energy exist in

various forms such as kinetic, potential, electrical, magnetic, nuclear,

etc. which have been generated from dierent sources. Similarly,

neurons that are present in the human central nervous system have the

ability to transmit the information in the form of electrical signals [13-

16]. Hence, bioeld is dened as a bioenergetic eld that permeates and

surrounds living organisms. Recently Prakash et al. reported that this

inherent biomagnetic eld around the human body can be measured

by few medical techniques such as Kirlian photography, polycontrast

interference photography and resonance eld imaging [17].

erefore, it is envisaged that human beings have the ability to

harness the energy from the environment/Universe and can transmit

into any object (living or non-living) around the Globe. e object(s)

will always receive the energy and responding in a useful manner

that is called bioeld energy. Mr. Trivedi's unique bioeld treatment

is also known as e Trivedi Eect® . It is known to transform the

characteristics of various living and non-living things. Moreover, the

bioeld treatment has caused signicant aect in dierent elds such

as agriculture [18-20] and microbiology [21-22].

e present work is focused to study the impact of Mr. Trivedi'

bioeld energy treatment on physical, thermal and spectral properties

of DHBP and characterized by XRD, DSC, TGA, particle size, surface

area, FT-IR and UV-visible spectroscopic analysis.

2,4-Dihydroxybenzophenone (DHBP) was procured from S D Fine

Chemicals Ltd, India. e sample was divided into two parts; one was

kept as a control sample while the other was subjected to Mr. Trivedi's

unique bioeld treatment and coded as treated sample. e treated

group was in sealed pack and handed over to Mr. Trivedi for bioeld

energy treatment under standard laboratory conditions. Mr. Trivedi

provided the energy treatment through his energy transmission

process to the treated group without touching the sample. e control

and treated samples were characterized by XRD, DSC, TGA, particle

size, surface area, FT-IR, and UV-visible analysis.

X-ray diraction (XRD) study

e XRD analysis of control and treated DHBP was carried out on

Phillips, Holland PW 1710 X-ray diractometer system, which had a

copper anode with nickel lter. e radiation of wavelength used by

the XRD system was 1.54056 Å. e data obtained from this XRD were

in the form of a chart of 2θ vs. intensity and a detailed table containing

peak intensity counts, d value (Å), peak width (θ°), relative intensity

(%) etc. e average crystallite size (G) was calculated by using formula:

Here, λ is the wavelength of radiation used, b is full width half-

maximum (FWHM) of peaks and k is the equipment constant (=0.94).

e molecular weight of atom was calculated using following

Molecular weight = number of protons x weight of a proton +

number of neutrons x weight of a neutron + number of electrons x

weight of an electron.

Molecular weight in g/Mol was calculated from the weights of

Treated 2,4-Dihydroxybenzophenone. Clin Pharmacol Biopharm 4: 145. doi:10.4172/2167-065X.1000145

Volume 4 * Issue 4 * 1000145

ISSN: 2167-065X CPB, an open access journal

e FT-IR spectra were recorded on Shimadzu's Fourier transform

infrared spectrometer (Japan) with the frequency range of 4000-500

cm-1 . e analysis was accomplished to evaluate the eect of bioeld

treatment at an atomic level like dipole moment, force constant and

bond strength in chemical structure [23]. e treated sample was

divided into two parts T1 and T2 for FT-IR analysis.

UV-Vis spectroscopic analysis

UV spectra of the control and treated DHBP samples were recorded

on Shimadzu UV-2400 PC series spectrophotometer with 1 cm quartz

cell and a slit width of 2.0 nm. e analysis was carried out using

wavelength in the range of 200-400 nm and methanol was used as a

solvent. e UV spectra was analysed to determine the eect of bioeld

treatment on the energy gap of highest occupied molecular orbital and

lowest unoccupied molecular orbital (HOMO-LUMO gap) [23]. e

treated sample was divided in two parts T1 and T2 for the analysis.

XRD was used to investigate the crystalline nature of the control

and treated DHBP. Figure 1 shows the XRD diractogram of the

control and treated DHBP. XRD diractogram of the control DHBP

º, 18.13 º, 18.52 º, 25.64 º, 27.93 º, 34.85 º, 37.57 º and 44.34 º. However,

15.23 º , 18.13 º, 18.50 º, 25.63 º, 27.94 º, 34.75 º, 34.85 º, 37.56 º, and 44.34 º .

e intensity of XRD peaks present at Brags angle 2θ equal to 18.13 º ,

as compared to the control. is showed an increase in crystallinity of

the treated DHBP with respect to the control sample. It is proposed

that bioeld energy treatment might increase the long-range order of

the DHBP molecules that lead to the formation of the symmetrical

crystalline pattern as compared to the untreated sample [24]. Based

on XRD peaks, control and treated samples were indexed with the

monoclinic crystal structure.

e unit cell volume, crystallite size and change in molecular

weight were computed from the XRD diractogram, and results

are presented in Table 1. e unit cell volume of control DHBP was

1063.70 10-24 × cm3 and it was minimally decreased to 1063.20 10-24 ×

cm3 in the treated sample. e treated DHBP showed a decrease in unit

cell volume by 0.05% as compared to the control sample. e molecular

weight (number of proton and neutrons) in control DHBP was 214.95

g/mol and it was minimally decreased up to 214.84 g/mol in the treated

sample. e treated sample showed 0.048 % change in molecular

weight with respect to control. It is hypothesized that bioeld energy

may be acted on the treated DHBP crystals at nuclear level and altered

the number of proton and neutrons as compared to the control, which

may lead to change in its molecular weight [25].

e crystallite size is known as a group of molecules or atoms

having the same orientation in one plane. Moreover, the crystallite

size is one of the crystallographic factors associated with the formation

of dislocations and point defects in the crystalline structure, which

directly inuences the material properties [26]. e crystallite size of the

control sample on the plane corresponding to most intense XRD peak

(i.e. 2θ = 27.9) was 78.08 nm, and it was remained unchanged in treated

DHBP sample (78.08 nm). Nevertheless, the average crystallite size was

also calculated from the XRD diractograms and data are presented

in Table 1. e average crystallite size of control DHBP was 62.19 nm,

and it was signicantly increased to 82.55 nm, in the treated sample.

e result showed an increase in average crystallite size by 32.73% in

treated sample as compared to the control. Caruntu et al. reported that

dielectric properties of barium powder could be varied by modulating

the crystallite size through an annealing process [27]. Vucinic-Vasic

et al. during their studies on zinc ferrite nanoparticles revealed that

crystallite size increases with elevation in annealing temperature [28].

Additionally, recently it was showed that introduction of ultrasound

to materials leads to substantial increase in crystallite size [29]. Hence,

it is assumed that bioeld treatment may provide waves similar like

ultrasound or thermal energy to treated DHBP atoms that led to a

decrease in dislocation densities and increase in crystallite size with

DSC study: DSC was used to investigate the melting point and

latent heat of fusion of control and treated DHBP. DSC thermogram

of the control and treated DHBP are presented in Figure 2. DSC

thermogram of the control DHBP showed a sharp melting endothermic

peak at 146.39 ºC, and it indicated the crystalline nature of the control

DHBP. However, the treated DHBP showed a minimal decrease in

melting endothermic peak and it was observed at 146.21º C.

e latent heat of fusion of control and treated samples were

obtained from respective thermograms and data are presented in

Figure 1: XRD diffractogram of control and treated 2,4-dihydroxybenzophenone.

# data[].attributes.attachment_link.title
Physical, Thermal and Spectral Properties of Biofield Energy Treated 2,4-Dihydroxybenzophenone - PdfSR.com

# data[].attributes.attachment_link.description
Study background: 2,4-Dihydroxybenzophenone (DHBP) is an organic compound used for the synthesis of pharmaceutical agents. The objective of this study was to investigate the influence of biofield energy treatment on the physical, thermal and spectral properties of DHBP. The study was performed in two groups (control and treated).

# data[].attributes.headline
	
	
		
			Biofield | Effect on Spectral Properties of 2,4-Dihydroxybenzophenone
		
	

# data[].attributes.subject
	
	
		
			Biofield | Effect on Spectral Properties of 2,4-Dihydroxybenzophenone
		
	

# data[].attributes.body
Dihydroxybenzophenone (DHBP) is used as UV-light absorber in resinous and polymer compositions such as polystyrene, acrylonitrile polymer and other copolymers. Read this study to know the biofield energy effect of DHBP.

# data[].attributes.attachment_link.keywords[]
physical properties of 2 4-dihydroxybenzophenone

# data[].attributes.attachment_link.title
"Physical, Thermal and Spectral Properties of Biofield Energy Treated 2,4-Dihydroxybenzophenone" by Mahendra Kumar Trivedi

# data[].attributes.attachment_link.description
Study background: 2,4-Dihydroxybenzophenone (DHBP) is an organic compound used for the synthesis of pharmaceutical agents. The objective of this study was to investigate the influence of biofield energy treatment on the physical, thermal and spectral properties of DHBP. The study was performed in two groups (control and treated).

# data[].attributes.headline
	
	
		
			Biofield & its Effect on Dihydroxybenzophenone Compound
		
	

# data[].attributes.subject
	
	
		
			Biofield & its Effect on Dihydroxybenzophenone Compound
		
	

# data[].attributes.body
Read more about the effect of Mahendra Kumar Trivedi biofield energy and biofield treatment on the physical, thermal and spectral properties of 2,4-Dihydroxybenzophenone.

# data[].attributes.headline
An Impact of Biofield Treatment on Dihydroxybenzophenone

# data[].attributes.subject
An Impact of Biofield Treatment on Dihydroxybenzophenone

# data[].attributes.body
An impact of Biofield treatment on 2,4-Dihydroxybenzophenone. Dihydroxybenzophenone is an organic compound used for the synthesis of pharmaceutical agents.

# data[].attributes.attachment_link.keywords[]
biofield - mahendra kumar trivedi - mahendra trivedi - trivedi effect - ultra violet-visible spectroscopy - laser particle size analyser - 2

# data[].attributes.attachment_link.title
Physical, Thermal and Spectral Properties of Biofield Energy T...

# data[].attributes.attachment_link.description
Physical, Thermal and Spectral Properties of Biofield Energy Treated 2,4-Dihydroxybenzophenone: Study background: 2,4-Dihydroxybenzophenone (DHBP) is an organic

# data[].attributes.headline
	
	
		
			Biofield Energy Treated Dihydroxybenzophenone Compound
		
	

# data[].attributes.subject
	
	
		
			Biofield Energy Treated Dihydroxybenzophenone Compound
		
	

# data[].attributes.body
Mahendra Kumar Trivedi main objective on present study was to study the effect of biofield energy on physical, thermal and spectral properties of 2,4-Dihydroxybenzophenone.

# data[].attributes.headline
	
	
		
			Biofield Treatment on Dihydroxybenzophenone Compound | Academia.edu
		
	

# data[].attributes.subject
	
	
		
			Biofield Treatment on Dihydroxybenzophenone Compound | Academia.edu
		
	

# data[].attributes.body
The aim of present study was to investigate the impact of Mahendra Kumar Trivedi biofield treatment on spectral properties 2,4-Dihydroxybenzophenone organic compound.

# data[].attributes.attachment_link.title
Physical, Thermal and Spectral Properties of Biofield Energy Treated 2,4-Dihydroxybenzophenone

# data[].attributes.attachment_link.description
Study background: 2,4-Dihydroxybenzophenone (DHBP) is an organic compound used for the synthesis of pharmaceutical agents. The objective of this study was to investigate the influence of biofield energy treatment on the physical, thermal and spectral