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Medical Scientists: Jobs, Career, Salary and Education Information

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Medical scientists conduct research aimed at improving overall human health. They often use clinical trials and other investigative methods to reach findings.

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According to the Centers for Disease Control and Prevention, more than 30 million Americans have diabetes - representing nearly 10 percent of our population. Those with Type 1 (insulin dependent) diabetes must inject daily insulin in order to survive. While Type 2 diabetes is far more common than Type 1, nearly one-third of those with Type 2 must also inject insulin on a daily basis. For some, the cost of diabetic supplies - particularly insulin - can lead to negative health consequences. In the last several decades, insulin prices have skyrocketed.

Insulin, discovered in 1921 has no generic competitors - only brand-name products are produced. A new study was presented in late June at the American Diabetes Association's annual scientific sessions showing that the cost of insulin results in nearly 25 percent of patients not taking insulin as they should. "Self-rationing" of insulin by patients can result in serious and potentially life-threatening complications such as blindness, loss of limbs, kidney failure and even death. Many patients are going to pharmacies only to find out that they must pay hundreds - if not thousands - of dollars for insulin.
What Is Diabetes? A Quick Primer
Diabetes occurs when your body can no longer handle sugars as they're ingested as food or drink. In Type 1 diabetes, the pancreas (an organ which makes insulin) no longer functions properly, and the only solution is to use artificially produced insulin either from injections or from an insulin pump. In Type 2 diabetes, the body can no longer respond to insulin and becomes "resistant." In both types, blood sugar fluctuations can be harmful to multiple organs and create lifelong complications. While there's no cure for Type 1 diabetes, Type 2 can be reversed with diet, weight loss and exercise (in some cases). All patients with Type 1 diabetes must have daily insulin - some with Type 2 diabetes require insulin, while others can be treated with oral medications.
Why Is Insulin So Expensive?
Insulin is a biologic compound that can be difficult and expensive to produce. There are several reasons it's become increasingly expensive - some are due to the biology and process involved in the manufacturing, and some are related to government regulations and the pharmaceutical industry's desire to continue to make a profit. From a biologic standpoint, insulin is created for human use by either "growing" an animal pancreas to produce insulin suitable for injection or by using recombinant DNA techniques that create bacteria that can produce large amounts of insulin for human use. Almost all insulin is created through the use of recombinant DNA techniques. Historically, pharmaceutical companies have simply made modifications to existing insulin types rather than work on the production of a "generic" or biosimilar product. While certainly possible, it's a bit more complicated to create a biosimilar form of insulin that would meet the standard for Food and Drug Administration approval. Moreover, the development of a generic or biosimilar insulin would be incredibly costly for the manufacturer but of a great benefit to patients.

From a regulatory perspective, insulin makers are protected from generic competitors under patent law. A patent allows a manufacturer to sell a product unchallenged for a certain number of years prior to approving a generic. In many cases, insulin makers continue to "tweak" current insulin products in order to extend their exclusivity rights. In addition, there's little incentive for pharmaceutical companies to spend millions of dollars to develop a cheaper alternative. Because insulin is considered a "biologic" drug, the FDA approval process is far more stringent and can take much longer than for other types of drugs. In addition, the FDA process is very costly for drug manufacturers. In the case of most generic alternatives, the generic can reduce costs by nearly 80 percent. In the case of insulin (because even a generic is expensive to produce), it's estimated that a generic form will only reduce costs by 20 percent. Unfortunately, it's my belief that the large manufacturers of insulin - Sanofi, Eli Lilly and Novo Nordisk - are working to make the development of generic insulins more difficult. In fact, Sanofi has filed lawsuits against both Merck and Mylan to prevent them from going to market with a generic lantus insulin (the Sanofi blockbuster drug).
What Can Be Done? A Call to Action
The patents on the latest insulin analogues are expiring, and there's now a pathway for FDA approval. There are biosimilar forms of insulin that have been approved in Europe, and some are available in the U.S. A class action lawsuit has been filed against all three manufacturers of insulin, accusing them of setting artificially high prices in order to provide certain insurance providers with preferred discounts - most of which don't get passed on to the patient.

For patients, it's important to take action:

1. Talk to your doctor about switching to a less expensive insulin. Make sure you're taking the type of insulin that's best for you at the best price point. And ensure your brand of insulin is on your insurance company's formulary.

2. Work with your local, state and U.S. representatives to effect legislative change to better regulate pharmaceutical companies and streamline FDA approval process for generic insulins.

3. Get involved with patient advocacy groups and work together to lower insulin prices. Patient-centered organizations are critical to effecting change.

4. Never attempt to save money by cutting your insulin dose. Take your medications as directed. If you're having trouble affording your medicine, talk to your doctor right away, and work to find a solution together.

Best Diabetes Diets

DIET Ranking information as of June 27th, 2018

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Insulin Costs Are Skyrocketing. This Is Why.

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According to the Centers for Disease Control and Prevention, more than 30 million Americans have diabetes - representing nearly 10 percent of our population. Those with Type 1 (insulin dependent) diabetes must inject daily insulin in order to survive.

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People with Type 2 Diabetes shouldn't have to pay for his because it's a necessity for them to survive. If it we didn't have inulin shots/pumps almost a whole quarter of our population would be dead!!

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Unfortunately the medication costs a lot of money. For the medication without insurance it could cost up to $6,500 with insurance it could cost almost half of that

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Type 2 diabetes happens because of you pancreas. It is caused when the pancreas produces little to no insulin.

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How Much Does an Insulin Pump Cost? - CostHelper.com

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How much you can expect to pay out of pocket for an insulin pump, including what people paid in 2018. According to the Academy of Managed Care Pharmacy, insulin pumps cost between $4,500 and $6,500 for individuals without insurance. The price varies depending upon the features, brand and size of the pump.

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Treatment and Management of Type 2 Diabetes

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An insulin pump is another form of the medication they need.They are practically the same thing. The difference is that you have to keep it on for 3 days then change it. It also has a small needle in it to insert the insulin. These are also very expensive and contain more

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Diabetes is the Greek term for "passing through," a phrase used to describe multiple diseases characterized by excessive urination. There are multiple forms of diabetes. The most frequently described is diabetes mellitus, a chronic disorder involving the body's use of blood glucose (blood sugar) and the synthesis, or utility, of the hormone insulin.

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The Advantages and Disadvantages of Using Insulin Pumps

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According to Dr. Saudek, the advantages to these pumps are that they stay in place, are cosmetically acceptable, and would make users less susceptible to infection than externally worn pumps do. The insulin these pumps deliver goes preferentially to the liver-just like insulin from a healthy pancreas does-which is thought to provide better blood sugar control with less hypoglycemia.

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this is one type of their medication that should be free, without this they could die. It also doesn't help with the fact that its extremely expensive.Some people might not have enough money and they could pass away since they won't be able to get the proper amount of insulin. (it could put them in a coma.)