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Microplastic particles found in human organs by US scientists | Environment | The Guardian

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Microplastic and nanoplastic particles are now discoverable in human organs thanks to a new technique.

Microplastics have polluted the entire planet, from Arctic snow and Alpine soils to the deepest oceans. People are also known to consume them via food and water, and to breathe them in, but the potential impact on human health is not yet known.

The researchers expect to find the particles in human organs and have identified chemical traces of plastic in tissue. But isolating and characterising such minuscule fragments is difficult, and contamination from plastics in the air is also a challenge.

Microplastics, defined as pieces of plastic smaller than 5mm in size, are shed by synthetic clothing being washed, vehicle tyres, and the spillage of plastic pellets used by manufacturers. The physical breakdown of plastic litter also creates them. Rain washes them into rivers and the sea, but they can also be blown by the wind, spread by flying insects, and end up in fields when treated sewage waste is used as fertiliser.

Studies have found microplastics in bottom-living sea creatures and sediments taken from the North Sea. Once ingested by small creatures, the microplastics move through the food chain. A study found microplastics in every one of 50 marine mammals washed up on UK shores, and the pollution is also ending up in humans.

In 2018 the World Health Organisation announced a review into the potential risks of plastic in drinking water after analysis found that more than 90% of the world's most popular bottled water brands contained tiny pieces of plastic. The UK banned plastic microbeads in cosmetics and personal care products in January 2019, and the EU has proposed new measures to curb their use.

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To test their technique, they added particles to 47 samples of lung, liver, spleen and kidney tissue obtained from a tissue bank established to study neurodegenerative diseases. Their results showed that the microplastics could be detected in every sample.

The scientists, whose work is being presented at a meeting of the American Chemical Society on Monday, said their technique would enable other researchers to determine contamination levels in human organs around the world.

"It would be naive to believe there is plastic everywhere but just not in us," said Rolf Halden at Arizona State University. "We are now providing a research platform that will allow us and others to look for what is invisible - these particles too small for the naked eye to see. The risk [to health] really resides in the small particles."

The analytical method developed allows the researchers to identify dozens of types of plastic, including the polyethylene terephthalate (PET) used in plastic drinks bottles and the polyethylene used in plastic bags.

They found bisphenol A (BPA), a chemical used to make plastics, in all 47 samples. The US Environmental Protection Agency is concerned about BPA because "it is a reproductive, developmental and systemic toxicant in animal studies". The researchers examined lung, liver, spleen and kidney tissue as these organs are likely to be exposed to microplastics or collect them.

"We never want to be alarmist, but it is concerning that these non-biodegradable materials that are present everywhere [may] enter and accumulate in human tissues, and we don't know the possible health effects," said Varun Kelkar of Arizona State University, part of the research team.

"Once we get a better idea of what's in the tissues, we can conduct epidemiological studies to assess human health outcomes," he said. "That way, we can start to understand the potential health risks, if any."

Charles Rolsky, another member of the team, said: "In a few short decades, we've gone from seeing plastic as a wonderful benefit to considering it a threat."

Microplastics are those less than 5mm in diameter and nanoplastics have a diameter of less than 0.001mm. Both form largely from the abrasion of larger pieces of plastic dumped into the environment. Research in wildlife and laboratory animals has linked exposure to tiny plastics to infertility, inflammation and cancer.

The researchers are now testing tissues to find microplastics that accumulated during donors' lifetimes. Donors to tissue banks often provide information on their lifestyles, diets and occupations, so this may help future work to determine the main ways in which people are exposed to microplastics.

The new methodology developed by the team to extract plastics from the tissues and analyse them will be shared online so other researchers can report their results in a standardised way. "This shared resource will help build a plastic exposure database so that we can compare exposures in organs and groups of people over time and geographic space," said Halden.

Previous studies have shown people eat and breathe in at least 50,000 particles of microplastic a year and that microplastic pollution is raining down on city dwellers, with London, UK, having the highest level of four cities analysed last year. The particles can harbour toxic chemicals and harmful microbes and are known to harm some marine creatures.

Other work has shown different kinds of nanoparticles from air pollution are present in human hearts and brains, and have been linked to brain cancer.

This article was updated on 17 August 2020, after more information was provided to the Guardian by the researchers, to reflect the fact that the plastic particles had been inserted into the samples of human tissue.

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Microplastic particles now discoverable in human organs

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New technique expected to enable scientists to find accumulated microplastics in humans

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Get ready for your exams with this BBC Bitesize GCSE Chemistry bonding, structure and the properties of matter (AQA) exam preparation guide.

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The three are solid, liquid and gas. The represents by small, solid spheres. It describes the arrangement, movement and of particles in a substance. The model can be used to explain the of solids, liquids and gases.

Explaining properties

A single particle does not have the properties of the material it is part of. The properties of a substance are the properties of a huge number of particles together.

have a fixed shape and cannot flow, because their particles cannot move from place to place

cannot be (squashed), because their particles are close together and have no space to move into

flow and take the shape of their container, because their particles can move around each other

cannot be compressed, because their particles are close together and have no space to move into

flow and completely fill their container, because their particles can move quickly in all directions

can be compressed, because their particles are far apart and have space to move into

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Solids, liquids and gases - The three states of matter - AQA - GCSE Chemistry (Single Science) Revision - AQA - BBC Bitesize

# data[].attributes.attachment_link.description
The three are solid, liquid and gas. The represents by small, solid spheres. It describes the arrangement, movement and of particles in a substance. The model can be used to explain the of solids, liquids and gases. A single particle does not have the properties of the material it is part of.