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Fibrinogen and thrombin can be combined in dry form without initiating a typical clotting reaction. Products containing these proteins in dry form have a variety of potential biomedical applications including topical hemostasis, tissue repair, drug delivery, etc. A significant benefit of these products is that they can be stored at room temperature and do not require thawing, reconstitution or device loading, so they are ready to use immediately when needed and well suited for use in emergent situations [3].

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What is collagen and what does it do?

Collagen is the body's most abundant protein, made up of amino acids, or peptides. It literally glues our bones, cartilage, skin, and blood vessels together. It's what makes our tissues grow, mature, and move. Its presence under your skin can keep it from sagging over time.Also called the remodelling stage of wound healing, the maturation phase is when collagen is re modeled from type III to type I and the wound fully closes. The cells that had been used to repair the wound but which are no longer needed are removed by apoptosis, or programmed cell death.

Type 1

Type I makes up 75-90% of the collagen found in your skin, hair, nails, organs, bone, ligaments. For skin and beauty applications Type I Collagen is considered to be the best.

Type 3

Type III Collagen is the second most abundant collagen in tissues; most commonly in tissues with elastic properties such as skin, lungs, intestinal walls and walls of blood vessels. It's also found in fibrous protein in bone, cartilage, dentin (a strengthening coating on teeth), tendons, and other connective tissues.

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What are platelets?
Platelets, or thrombocytes, are small, colourless cell fragments in our blood that form clots and stop or prevent bleeding. Platelets are made in our bone marrow, the sponge-like tissue inside our bones.

What is the function of platelets?
In addition to being the smallest blood cell, platelets are also the lightest.  Therefore they are pushed out from the centre of flowing blood to the wall of the blood vessel.  There they roll along the surface of the vessel wall, which is lined by cells called endothelium.  The endothelium is a very special surface, like Teflon, that prevents anything from sticking to it.  However when there is an injury or cut, and the endothelial layer is broken, the tough fibres that surround a blood vessel are exposed to the liquid flowing blood.  It is the platelets that react first to injury.  The tough fibres surrounding the vessel wall, like an envelop, attract platelets like a magnet, stimulate the shape change that is shown in the pictures above, and platelets then clump onto these fibres, providing the initial seal to prevent bleeding, the leak of red blood cells and plasma through the vessel injury.

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How is Fibrin related to sports injuries?
Fibrin forms strands that grow into the network somewhat like a fish net. The fibrin net captures circulating platelets and forms a plug that seals the damaged vessel, sometimes completely plugging it so circulation through the damaged vessel stops. The area is left with a mass of whole blood and cellular debris which together are known as a hematoma.

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Plasmin is an important enzyme present in blood that degrades many blood plasma proteins, including fibrin clots.

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What is Neuroreceptors? Neurotransmitters are endogenous chemicals that enable communication within the nervous system and between the nervous system and the rest of the body. They relay information between individual neurons, and ultimately regulate a wide range of bodily functions.

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What is Neuroreceptors? Neurotransmitters are endogenous chemicals that enable communication within the nervous system and between the nervous system and the rest of the body. They relay information between individual neurons, and ultimately regulate a wide range of bodily functions.

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a soluble protein present in blood plasma, from which fibrin is produced by the action of the enzyme thrombin.

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Thrombin is a naturally occurring enzyme that converts fibrinogen into fibrin, which is an integral step in clot formation. In vivo thrombin is formed from prothrombin as a result of activation of both the intrinsic and extrinsic pathways of the coagulation cascade.

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What is it?
Fibrin is an insoluble protein that is produced in response to bleeding and is the major component of the blood clot. Fibrin is a tough protein substance that is arranged in long fibrous chains; it is formed from fibrinogen, a soluble protein that is produced by the liver and found in blood plasma. When tissue damage results in bleeding, fibrinogen is converted at the wound into fibrin by the action of thrombin, a clotting enzyme. Fibrin molecules then combine to form long fibrin threads that entangle platelets, building up a spongy mass that gradually hardens and contracts to form the blood clot.

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Neuroreceptors are found on the surface of cells and have numerous functions. They act as binding sites or antigens to antibodies and other ligand and can communicate signals within a cell or between cells and even allow for transport of molecules into and out of the cell.

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Neuroreceptors are found on the surface of cells and have numerous functions. They act as binding sites or antigens to antibodies and other ligand and can communicate signals within a cell or between cells and even allow for transport of molecules into and out of the cell.