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Students form small groups of 3-4 and create a choreographed dance/movement sequence representing different phases of the cell cycle. Each group performs in a small designated area:
- Interphase movements showing DNA replication
- Prophase chromosome condensation
- Metaphase alignment
- Anaphase separation
- Telophase and cytokinesis
Time: 20-25 minutes
Materials needed: Small space for each group

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In pairs, students observe prepared slides of onion root tips under microscopes to identify and count cells in different stages of mitosis:
1. Each pair gets 15 minutes at the microscope
2. Students draw and label what they observe
3. Calculate percentage of cells in each phase
4. Compare findings with other pairs
Time: 45 minutes
Materials: Microscopes, prepared slides

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Using play-dough or clay, students model the stages of mitosis:
1. Different colors for chromosomes, nuclear membrane, and cell membrane
2. Create and photograph each stage
3. Label key structures
4. Present mini-model to neighboring pair
Time: 30 minutes
Materials: Play-dough/clay, paper for labels

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In groups of 2-3, students create detailed timeline cards for each phase:
1. Each group gets specific phases to work on
2. Include timing, main events, and checkpoints
3. Add illustrations
4. Arrange cards in correct sequence
5. Present to another group
Time: 25 minutes
Materials: Index cards, markers

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Chromosome Simulation with Pipe Cleaners

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Chromosome Simulation with Pipe Cleaners

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Students use pipe cleaners to demonstrate chromosome behavior:
1. Different colors for maternal/paternal chromosomes
2. Model chromosome condensation and separation
3. Show crossing over during meiosis
4. Document each stage with diagrams
Time: 20 minutes
Materials: Pipe cleaners, worksheet for documentation

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Students time and compare different phases of the cell cycle using scaled time:
1. If interphase was 12 hours, calculate proportional times for other phases
2. Create a time wheel showing relative durations
3. Use stopwatch to act out phases in scaled time
Time: 15-20 minutes
Materials: Stopwatch, calculation sheets

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Students become cell cycle detectives:
1. Rotate between 3-4 microscope stations
2. Each station has different prepared slides
3. Identify and sketch cells in different phases
4. Create a digital or paper portfolio of findings
Time: 40 minutes
Materials: Microscopes, various prepared slides

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In pairs, students create a comic strip showing cell division:
1. Each frame shows a different phase
2. Include dialogue bubbles explaining what's happening
3. Add molecular details and checkpoints
4. Share with other pairs
Time: 30 minutes
Materials: Paper, colored pencils

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Small group role-play of proteins involved in cell cycle:
1. Students represent different proteins (cyclins, CDKs, etc.)
2. Act out interactions during each phase
3. Show checkpoint regulation
4. Create name tags with protein functions
Time: 25 minutes
Materials: Name tags, role cards

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Observe living yeast cells undergoing budding:
1. Prepare yeast culture in small groups
2. Observe under microscopes
3. Count cells in different stages
4. Graph results
5. Discuss factors affecting division rate
Time: 45 minutes
Materials: Microscopes, yeast culture supplies, graph paper