# data[].attributes.body
Wang, X., Zhang, D., Yogendra Pratap Singh, Yeo, M., Deng, G., Lai, J., Chen, F., Ozbolat, I. T., & Yu, Y. (2024). Progress in Organ Bioprinting for Regenerative Medicine—Article. Engineering. https://doi.org/10.1016/j.eng.2024.04.023

Who we are. Organovo, Inc. (2024). https://organovo.com/about/who-we-are/

# data[].attributes.body
3D bioprinting uses technology to create living tissue, and someday, organs.

There are several different types of 3D bioprinting, each providing their unique abilities to create living tissue for drug testing, organ repair and full organs.

The three major types of bioprinting include Thermal Inkjet, Extrusion Based, and Vat photopolymerization. Natural and Synthetic polymers are the primary ink substrate consisting of polysaccharides, protein, or polyethylene glycol, polyurethane. Pre-differentiated cells are also part of the matrix (ink) and are chosen based on desired tissue type; this could include cardiac myocytes, fibroblasts, endothelial cells and immune cells (Wang et al., 2024).

Organovo currently uses this technology to create 3D tissue models of human bowel to "understand, invent, and develop the best drug therapies for irritable bowel syndrome and ulcerative colitis." Using bioprinted human tissue models, they can evaluate drug response and effectiveness. This technology improves testing and overall outcomes for human treatment versus animal testing. They have recently started phase 2 trials on their newest drug using 3D bioprinting technology (Organovo, 2024).

# data[].attributes.body
Bioprinted tissue can be specific to each patient

Off-the shelf organs instead of waiting for organ donor match

Negate the use of anti-rejection medications

Improve drug efficacy

Increase life expectancy

# data[].attributes.body
Regulatory requirements may delay process

Patient disease may prevent viable cells for Bioink matrix

High startup cost

# data[].attributes.body
The idea that we could have easy access to personalized organs for transplants, without a donor, is pretty amazing. Although we are not quite ready for whole organ printing, this technology has already begun to enhance care and improve patient outcomes.

We can now better understand the body's response to drug therapy and make them more efficacious. This could minimize damage to other organs and decrease the need for lifelong treatments. It could also bring us closer to a cure for cancer by testing treatments on printed tumor cells. My hope is that we can continue to develop this technology in a way that improves healthcare without a major price tag.

# data[].attributes.body
I chose the following team members: Fernando (Focus) because he is good at staying on track and setting goals; Daisy (Developer) because she can be a good helper and coach the team when needed; Pablo (Positivity) for his ability to be an optimistic and enthusiastic team member; Rachel (Restorative) for her ability to troubleshoot problems; and Sheila (Strategic) because she can plan for the unexpected and make good judgement calls.

Along with my strengths (Relator, Arranger, Responsibility, Learner, Self-Assurance), I believe each team member brings a different skill set that can motivate, stay focused and work well together to achieve the goals we have set.