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The Science of Slowing Down Aging | WIRED

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A rare genetic mutation in the LMNA gene causes children with Progeria to age decades within just a few years. Despite the physical changes, their minds and personalities remain bright and strong—offering powerful insight into both resilience and the biology of aging.

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A rare genetic mutation in the LMNA gene causes children with Progeria to age decades within just a few years. Despite the physical changes, their minds and personalities remain bright and strong—offering powerful insight into both resilience and the biology of aging.

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A change in one gene causes progeria. This gene, known as lamin A (LMNA), makes a protein that's needed to hold the center of a cell, called the nucleus, together. When the LMNA gene has a change, a flawed lamin A protein called progerin is made. Progerin makes cells unstable and appears to lead to progeria's aging process.

# data[].attributes.wish_content.attachment_props.alternative_text
A change in one gene causes progeria. This gene, known as lamin A (LMNA), makes a protein that's needed to hold the center of a cell, called the nucleus, together. When the LMNA gene has a change, a flawed lamin A protein called progerin is made. Progerin makes cells unstable and appears to lead to progeria's aging process.

# data[].attributes.wish_content.attachment_props.alternative_text
A change in one gene causes progeria. This gene, known as lamin A (LMNA), makes a protein that's needed to hold the center of a cell, called the nucleus, together. When the LMNA gene has a change, a flawed lamin A protein called progerin is made. Progerin makes cells unstable and appears to lead to progeria's aging process.