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The RER can be found in both plant and animal cells. It is continuous with the nuclear envolope and located within close proximity of the golgi apparatus. Some proteins don't leave the ER and have their own function there. Cells from a pancreas or liver have large ER systems.

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https://www.genome.gov/genetics-glossary/Endoplasmic-Reticulum-rough

http://www.biology4kids.com/files/cell_er.html

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The RER plays a large role in the synthesis of proteins. It is a manufacturing and packaging system. It works with the golgi apparatus, ribosomes, tRNA, and mRNA. The membrane form sacs called cisternae where the protein is actually synthesized. When a protein is complete, it is pinched off in a vesicle.

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The smooth ER doesn't even have Ribosomes. Talk about a Loser. Where would the ribosomes be located if the RER was not there? How would cells synthesize proteins without the rough ER? This makes the protein. Cells would be weak without me!

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There is only one main problem I could think of when it came to the RER. Misfolded Proteins. They lead to ER stress, then cell dysfunction, and cell death.

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The Rough Endoplasmic Reticulum is a series of flattened sacs and are part of a continuous membrane organelle. It almost looks like a maze or ribbon with many small bumps covering its surface. These small bumps are called ribosomes. One might say its membrane looks like sheets or discs as well.

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The RER synthesizes proteins, then packaged into vesicles and sent to the Golgi apparatus. The Protein is assembled from an RNA sequence. After that it is carried by a ribosome into the RER. Membrane. The protein either goes to the RER membrane or RER lumen. It goes to the lumen if the protein is water soluable.