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http://www.nature.com/mt/journal/v16/n2/full/6300351a.html

Gene therapy and viral vectors

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https://books.google.co.uk/books?id=vA2fFx4Xv7oC&pg=PA139&lpg=PA139&dq=MYO15&source=bl&ots=cIzW4WQDzI&sig=M95OvXDF_2T1mYU0fW8xgLuJCPM&hl=en&sa=X&ved=0ahUKEwjr2rDVmsXKAhUG1xQKHcMSDR8Q6AEIYzAO#v=onepage&q=MYO15&f=false

page 138 - role of myosin

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Myosin 15 is a molecular motor protein, so called because it can move around within a cell. Scientists believe that myosin 15 helps to build stereocilia by supplying them with components for assembly, much like a delivery truck. But the molecular structure of myosin 15 and how it functions in stereocilia assembly is still unclear. To gain a better understanding of how myosin 15 works, the researchers set out to produce and purify the protein.

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- Info on genetic disorder

- biochemical function of mutated gene

- molecular basis of the disease

- methods of detecting mutation

- gene therapy?

- conclusion