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Bio safety concerns of biomaterial which may cause unknown side effects to human body

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source of the materials
pricing
whether the therapeutics will have a chance of causing rare disease （low possibility，might not occur during clinical trial

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Ensure the safety when doing clinical trials
Don't mislead the customers
Respect the IP
Adhere to research evidences

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-information regarding clinical trials
-pricing inequality for biomaterial-based therapy
-Patients have the right to know what the drug cam do but the information is often disclosed.

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company doesn’t explain side effect or even device failure clearly (?)

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Animal may sacrifice for trials of biomaterials.

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Animal experiments
Controversy around Neuralink

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- a lot of animals involved before going to human
- not enough research before clinical trials since the companies want to go to market asap (can harm patients’ health)

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1) Affordability/accessibility - too high price, limited distribution
2) research misconduct
3) clinical trials - choice of patients/ choice of placebo

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The over-promotion may lead to drug abuse.

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Sometimes a certain therapy works better for one race than another.

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- ethical to manipulate genes to alter/ create lives?
- companies may be discouraged to develop drugs that are less profitable like antibiotics due to market influence
- using animal testing
- different laws and different countries where biomaterials are produced/ sold

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For biomaterials that might use another animal’s cells, there could be ethical matters rising from sacrificing animals for therapeutic gain. In terms of IP, companies may keep life-saving medication instead of allowing it for mass production (e.g. the COVID vaccine)

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Source of raw materials (animal based)
How much disclosed about clinical trials

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Animal derived components that may need to sacrifice animals

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Sometimes companies may place monetary gain over patient or public health. This may lead to monopolization of therapies that people may need in order to live or improve their quality of life
At the same time, it costs a lot to develop and manufacture drugs