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What is the genotype for people with this condition?

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What is the genotype for people with this condition?

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1. It is a autosomal recessive disease
2. It affects the hemoglobin gene

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What is the phenotype for people with this condition?

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What is the phenotype for people with this condition?

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1. It is expressed by creating sickled red blood cells which are fragile and easily damaged, which come from a mutation in the hemoglobin gene. These sickled red blood cells can also clog blood vessels due to their abnormal size. Anemia happens because the sickled cells are usually destroyed before their life is completed this creates a shortage in red blood cells which cannot supply enough oxygen to the body.

2.  The symptoms are having oxygen concentration drop when exercising and having red blood cells stick together. Also sickle cells may jam capillaries, cause blood clots, Paralyzing strokes may occur if blood cannot travel to the brain which means it will not be able to give oxygen.

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What is one interesting fact that you learned about this condition?

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What is one interesting fact that you learned about this condition?

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I learned that in the Africa that as many as 5% to 25% of sub-Saharan Africans and 8% of African Americans are heterozygous for sickle cell anemia. However, this disorder in Africa causes people to be resistant to malaria which gives them a “heterozygous advantage”.

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How is this condition passed from one generation to the next?

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How is this condition passed from one generation to the next?

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1. This gene is not sex-linked

2. Each parent would need to be either heterozygous or homozygous for the sickle cell gene.

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1. My Textbook

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1. This is a dominant disorder

2. It affects the Huntington gene

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What is the phenotype for people with this condition?

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What is the phenotype for people with this condition?

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1. The mutant Huntington interferes with the action of normal Huntington and forms large aggregates in nerve cells that ultimately kills the cells

2. The results and symptoms of this disease are loss of coordination, flailing movements, personality disturbances and eventual death.

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How is this condition passed from one generation to the next?

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How is this condition passed from one generation to the next?

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1. This gene is not sex linked

2. Would either need to be heterozygous or homozygous for the gene

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It is a rare disease named after George Huntington. About 30,000 people in the USA have this disease and 200,000 people are at risk of getting it.

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https://www.alz.org/alzheimers-dementia/what-is-dementia/types-of-dementia/huntington-s-disease

Chapter 10 Patterns Of Inheritance in the textbook

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What is the genotype for people with this condition?

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What is the genotype for people with this condition?

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1. This is a recessive disorder.
2. It affects the F8 gene.

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What is the phenotype for people with this condition?

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What is the phenotype for people with this condition?

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1. Hemophilia is expressed by an inherited tendency for the blood to not clot properly. This can cause bleeding of its own as well as bleeding after an accident or surgery.

2. Symptoms include bleeding into the joints which can cause swelling and pain or tightness in the joints. Bleeding into the skin (bruising) or muscle and soft tissue causing a build-up of blood in the area  (a hematoma). Bleeding of the mouth and gums, and bleeding that is hard to stop after losing a tooth. Blood in the urine or stool.

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How is this condition passed on from one generation to the next?

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How is this condition passed on from one generation to the next?

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1. This gene is sex linked.

2. The mother's X chromosome with the hemophilia gene or her X chromosome with the usual blood clotting gene will be passed on to the baby.  Since the Y chromosome does not carry the hemophilia gene, a son born to a man with hemophilia and a woman who is not a carrier will not have hemophilia.

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What is one interesting fact you have learned about this condition?

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What is one interesting fact you have learned about this condition?

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I learned a couple of things. I learned that hemophilia affects about one out of every 5,000 males born. Hemophilia A is four times more common than hemophilia B, and about half of those who are infected have a moderate form of the condition. Hemophilia affects about 400,000 people globally, including only 20,000 people in the United States. Hemophilia is a blood disorder that affects individuals of both races and ethnicities.

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https://www.cdc.gov/ncbddd/hemophilia/facts.html
https://www.mayoclinic.org/diseases-conditions/hemophilia/symptoms-causes/syc-20373327

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What is the Genotype for people with this Condition?

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What is the Genotype for people with this Condition?

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1. This is passed down as a recessive disorder.
2. Albinism effects the P Gene.

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What is the Phenotype for people with this condition?

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What is the Phenotype for people with this condition?

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1. Albinism is expressed with very light skin and hair color than what is compared to their siblings if they don't have albinism. This causes skin that is very sensitive to UV rays from the sun.
2. Symptoms may include different eye conditions such as astigmatism, sensitivity to light, and extremely pale skin color.

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How is this condition passed from one generation to the next?

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How is this condition passed from one generation to the next?

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1. This gene is sex linked.
2. Both parents would have to have a recessive trait for albinism so heterozygous or homozygous recessive.

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What is one interesting fact learned about this condition.

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What is one interesting fact learned about this condition.

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I learned that Albinism is caused because the amount of melanin and pigment makes the skin, eyes and hair pale, and because of this there is no protection from sunlight.

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https://kidshealth.org/en/teens/albinism.html