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1. The Two Divisions of the ANS & Alternate Names:

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1. The Two Divisions of the ANS & Alternate Names:

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1. Sympathetic nervous system (cranialsacral division.)
2.Parasympathetic nervous system (thoracolumbar divison.)

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2. The Neurotransmitters For Each Division:

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2. The Neurotransmitters For Each Division:

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The Parasympathetic Nervous System neurotransmitter is acetylcholine (ACH.)
The Sympathetic Nervous System neurotransmitters are ACH & norepinephrine (NE.)

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3. The Locations Where Each NT Is Released In Each Division of the ANS.

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3. The Locations Where Each NT Is Released In Each Division of the ANS.

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The Parasympathetic Nervous System NT is released at the ganglia and postganglionic nerve endings.
The Sympathetic Nervous System NT's are released at the ganglia (ACH) amd postganglionic nerve endings (NE.)

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4. The Receptors Of Each Division With Main Locations Of Each Receptors:

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4. The Receptors Of Each Division With Main Locations Of Each Receptors:

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Parasympathetic Nervous System Receptors (Cholinergic Receptors): Muscarinic located on the cell membranes of the visceral organs and nicotinic (Nn & Nm.) Nn receptors are located at parasympathetic and sympathetic ganglia and Nm receptors are located on cell membranes of skeletal muscles.
Sympathetic Nervous System Receptors (Adrenergic Receptors:) Alpha and Beta receptors located on the postsynaptic membrane at the sympathetic junctions.

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5. The End Organ Responses That Occur When Each Transmitter Is Stimulated:

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5. The End Organ Responses That Occur When Each Transmitter Is Stimulated:

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Iris Muscle (Eye)- Contraction, pupillary dilation. Alpha-1 (Contraction of Smooth Muscle)
Heart- Greater increase in heart rate, force of contraction, and atrioventricular conduction. Beta-1 (Stimulation of Cardiac Muscle)
Uterus- Relaxation.
Beta-2 (Relaxation of Smooth Muscle)

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6. The Drug Classifications For Each Division of the ANS:

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6. The Drug Classifications For Each Division of the ANS:

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Sympathetic Nervous System- Sympathomimetic Drug Class stimulated by the Alpha-1 adrenergic receptors (relaxation of smooth muscle) along with Beta-1 (stimulates heart rate) & Beta-2 (relaxation of smooth muscle) receptors.
Parasympathetic Nervous System- Sympatholytic Drug Class interacts with Alpha-1 (decreased blood pressure), Beta-1 (decreased heart rate), Beta-2 (smooth muscle contraction), and adrenergic nerve ending (lowers blood pressure and cardiac function) receptors.

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1. Alpha-1 Adrenergic Agonists

norepinephrie (Levophed®)
midodrine (ProAmatine®)
2. Adrenergic Agonists
epinephrine (Adrenalin®, EpiPen®, Primatene Mist®)
3. Alpha-1 Adrenergic Agonist
alfuzosin (Uroxatral®)
silodosin (Rapaflo®)
4. Beta-1 Adrenergic Agonist
dobutamine
5. Beta-2 Adrenergic Agonist
formoterol (Foradil®)
albuterol (Proventil®/Ventolin®)
trbutaline (Brethine®)
6. Beta Blocker
Nonselective-
nadolol (Corgard®)
propranolol (Inderol®)
timolol (Brethine®)
Selective-
atenolol (Tenormin®)
metoprolol (Lopressor®)
7. Direct Acting Cholinergic Agonist
acetylcholine
pilocarpine (Pilocar®)
bethanechol (Urecholine®)
8. Indirect Acting Cholinergic Agents
neostigmine (Prostigmin®)
9. Anticholinergic
atropine
dicyclomine (Bentyl®)
10.Skeletal Muscle Relaxants
a. Peripherally Acting
Depolarizing Agent:
succinylcholine
Non-depolarizing Agent
rocuronium bromide (Zemuron®)
Direct Acting
dantrolene (Dantrium®)

b. Centrally Acting
cyclobenzaprine (Flexeril®)
carisoprodol (Soma®)
methocarbamol (Robaxin®)
orphenadrine citrate (Norflex®)
chlorzoxazone (Parafon Forte DSC®)
metaxalone (Skelaxin®)