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Bai Beacon "The Role of Genetics: Will I get Alzheimer's Disease?" Alzheimer's Prevention Registry. Family and Community Services, June 7, 2017. March 11, 2020
https://www.endalznow.org/news/the-role-genetics-will-i-get-alzheimers-disease

"Alzheimer disease - Genetics Home Reference - NIH" U.S. National Library of Medicine. May 2019. March 11, 2020
https://ghr.nlm.nih.gov/condition/alzheimer-disease

"Alzheimer's Disease: Genetics and Risk Factors" WebMD. May 5, 2019. March 11, 2020
https://www.webmd.com/alzheimers/guide/alzheimers-genetic#1

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Also, it can be managed by caregivers which is an option or putting the person with ALZ to a nursing home so that they could be taken care of in an a safe environment as ALZ progresses and worsens.

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Since Alzheimer's has no cure, there are some current ALZ medication for people with memory symptoms and and other cognitive changes. Two drugs that are currently use to treat cognitive symptoms are Cholinesterase Inhibitors. They are used to boost levels of cell-to-cell communication by preserving a chemical messenger t hat is depleted into the brain by Alzheimer's disease. They also improve neuropsychiatric symptoms, such as agitation or depression. When prescribed the Cholinesterase Inhibitors include donepezil (Aricept, galantamine (Razadyne and rivastigmine (Exelon). Another medication is Memantine (Namenda). It works in another brain cell communication network and slows the progression of the symptoms with moderate to severe AlZ. It sometimes in combination with a cholinsterase inhibitor.

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Alzheimer's is a disease as people grow old. Alzheimer's can impact a persons life heavily or mildly. An example will be experiencing greater memory loss, wandering/getting lost, etc.  Another impact would be is having a caregiver or getting put into a nursing home. Life with Alzheimer's is not easy because they have a lot of obstacle to get through. There stages 7 stages of Alzheimer's, Stage 1: No Impairment (not detectable), Stage 2: Very mild, Stage 3: Mild, Stage 4: Moderate decline, Stage 5: Moderately severe decline, Stage 6: Severe decline and Stage 7: Very severe decline.

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APOE comes in three forms: e2, e3, e4, and you get one from each parent. There are six different combinations which are e2/e2, e2/e3, e2/e4 e3/e3, e3/e4, e4/e4. e2 slightly reduces the risk of getting Alzheimer's while e4 is associated with the increased risk of getting it. While other genes do have an effect on the probability of getting Alzheimer's, APOE has the most effect.

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Late-Onset is found in people age 60 or older, and is much more common than Early-Onset. So far the genetic mutation for Late-Onset hasn't been found yet.

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Early-Onset is caused by gene mutations that have been passed from parent to offspring and is the result of mutations in one of these three genes, amyloid precursor protein gene, which gives "instructions" on how to make APP protein. In the DNA where Early-Onset Alzheimer's has been found, the flaws were found in related genes of chromosomes 1 and 14, and developed before the age 60. But it is much more rare to get Early-Onset Alzheimer's.

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Although there is evidence and research explaining how it is inherited, more research still needs to be done by scientists

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People without the APOE4 gene are more likely to get Alzheimer's. Although it APOE4 heightens the risk of getting the disease, it doesn't guarantee so.

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Between the APOE gene is where late-onset Alzheimer's is caused, while people with the APOE4 gene are more likely to get Alzheimer's earlier in life, but the probability isn't always guaranteed.

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Physiological: depression, hallucination or paranoia
Memory loss disrupting daily life, challenges in planning or solving problems, difficulty completing different familiar tasks, trouble understanding and spatial relationships, confusion with time and place, inability to combine muscle movement, jumbled, loss of appetite, new problems with words in speaking or writing, misplacing and losing the ability to retrace steps, decreased or poor judgement, withdrawal form work or social activities, changes in mood and personality.

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Alzheimer's is more likely to be inherited when he mother has it. It is inherited through mutations in the genes on chromosome 1, 14, 19, and 21

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Difference Between Alzheimer's and Dementia

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Difference Between Alzheimer's and Dementia

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Alzheimer's cannot be cured or reversed, while some forms of Dementia can be reversed, or cured.

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Behavioral: aggression, agitation, difficulty with self care, irritability, meaningless repetition of own words, personality changes, restlessness, lack of restraint, or wandering and getting lost.

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There are two types of Alzheimer's, early onset and late onset. Early onset is found in families that are younger, while late onset is found in people in their mid 60's

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Cognitive: mental decline, difficulty thinking and understanding, confusion in the evening hours, delusion, disorientation, forgetfulness, making things up, mental confusion, difficulty concentrating, inability to create new memories, inability to do simple math, or inability to recognize common things.

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Alzheimer's is a brain disorder that causes memory loss overtime. It gradually gets worse